Cdc14a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cdc14a
CDC14 cell division cycle 14A
MGI:2442676

29 phenotypes from 6 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cdc14a^em1Jgao/Cdc14a^em1Jgao CBA/CaJ-Cdc14a^em1Jgao	abnormal cochlear hair cell stereociliary bundle morphology	J:301219
	abnormal sperm head morphology	J:301219
	abnormal sperm nucleus morphology	J:301219
	absent sperm head	J:301219
	arrest of male meiosis	J:301219
	asthenozoospermia	J:301219
	coiled sperm flagellum	J:301219
	decreased cochlear hair cell number	J:301219
	decreased male germ cell number	J:301219
	decreased sperm progressive motility	J:301219
	impaired hearing	J:301219
	increased or absent threshold for auditory brainstem response	J:301219
	paternal effect	J:301219
	reduced male fertility	J:301219
	normal reproductive system phenotype	J:301219
	teratozoospermia	J:301219
Cdc14a^em1Tbf/Cdc14a^em1Tbf involves: C57BL/6J	cochlear hair cell degeneration	J:257652
	deafness	J:257652
	fused inner hair cell stereocilia	J:257652
	fused outer hair cell stereocilia	J:257652
	male infertility	J:257652
	oligozoospermia	J:257652
	preweaning lethality, incomplete penetrance	J:257652
	seminiferous tubule degeneration	J:257652
Cdc14a^{tm1a(EUCOMM)Hmgu}/Cdc14a^{tm1a(EUCOMM)Hmgu} C57BL/6N-Cdc14a^{tm1a(EUCOMM)Hmgu}	absent distortion product otoacoustic emissions	J:257652
	deafness	J:257652
	increased or absent threshold for auditory brainstem response	J:257652
	preweaning lethality, incomplete penetrance	J:257652
	sensorineural hearing loss	J:257652
Cdc14a^{tm1a(EUCOMM)Hmgu}/Cdc14a^{tm1b(EUCOMM)Hmgu} involves: C57BL/6N * FVB	absent distortion product otoacoustic emissions	J:257652
	cochlear hair cell degeneration	J:257652
	cochlear inner hair cell degeneration	J:257652
	cochlear outer hair cell degeneration	J:257652
	deafness	J:257652
	fused inner hair cell stereocilia	J:257652
	fused outer hair cell stereocilia	J:257652
	increased or absent threshold for auditory brainstem response	J:257652
	male infertility	J:257652
	oligozoospermia	J:257652
	preweaning lethality, incomplete penetrance	J:257652
	seminiferous tubule degeneration	J:257652
	sensorineural hearing loss	J:257652
	teratozoospermia	J:257652
Cdc14a^{tm1b(EUCOMM)Hmgu}/Cdc14a^{tm1b(EUCOMM)Hmgu} involves: C57BL/6N * FVB	absent distortion product otoacoustic emissions	J:257652
	cochlear hair cell degeneration	J:257652
	cochlear inner hair cell degeneration	J:257652
	cochlear outer hair cell degeneration	J:257652
	deafness	J:257652
	fused inner hair cell stereocilia	J:257652
	fused outer hair cell stereocilia	J:257652
	increased or absent threshold for auditory brainstem response	J:257652
	male infertility	J:257652
	oligozoospermia	J:257652
	preweaning lethality, incomplete penetrance	J:257652
	normal reproductive system phenotype	J:257652
	seminiferous tubule degeneration	J:257652
	sensorineural hearing loss	J:257652
	teratozoospermia	J:257652
Cdc14a^{tm1d(EUCOMM)Hmgu}/Cdc14a^{tm1d(EUCOMM)Hmgu} involves: C57BL/6N * FVB	absent distortion product otoacoustic emissions	J:257652
	cochlear hair cell degeneration	J:257652
	cochlear inner hair cell degeneration	J:257652
	cochlear outer hair cell degeneration	J:257652
	deafness	J:257652
	fused inner hair cell stereocilia	J:257652
	fused outer hair cell stereocilia	J:257652
	increased or absent threshold for auditory brainstem response	J:257652
	male infertility	J:257652
	oligozoospermia	J:257652
	preweaning lethality, incomplete penetrance	J:257652
	normal reproductive system phenotype	J:257652
	seminiferous tubule degeneration	J:257652
	sensorineural hearing loss	J:257652
	teratozoospermia	J:257652
Cdc14a^{tm1e.1(EUCOMM)Hmgu}/Cdc14a⁺ B6N(Cg)-Cdc14a^{tm1e.1(EUCOMM)Hmgu}/J	cataract	J:211773
Cdc14a^{tm1e.1(EUCOMM)Hmgu}/Cdc14a^{tm1e.1(EUCOMM)Hmgu} B6N(Cg)-Cdc14a^{tm1e.1(EUCOMM)Hmgu}/J	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23