About   Help   FAQ
Due to maintenance, access to MGI may be intermittent 7:30-8:30 AM EDT Thursday, May 28.
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Dusp4
dual specificity phosphatase 4
MGI:2442191
25 phenotypes from 4 alleles in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Dusp4Gt(XG164)Byg/Dusp4Gt(XG164)Byg
B6.129P2-Dusp4Gt(XG164)Byg
normal immune system phenotype J:180366
increased CD4-positive, alpha beta T cell number J:180366
increased interleukin-10 secretion J:180366
increased T cell proliferation J:180366
Dusp4tm1a(EUCOMM)Wtsi/Dusp4tm1a(EUCOMM)Wtsi
C57BL/6N-Dusp4tm1a(EUCOMM)Wtsi/Wtsi
decreased caudal vertebrae number J:175295
decreased circulating glucose level J:175295
decreased circulating potassium level J:175295
decreased circulating sodium level J:175295
decreased lumbar vertebrae number J:175295
decreased rib number J:175295
decreased thoracic vertebrae number J:175295
increased circulating sodium level J:175295
increased sacral vertebrae number J:175295
Dusp4tm1Jmol/Dusp4tm1Jmol
involves: 129
decreased B cell apoptosis J:140567
Dusp4tm1Plev/Dusp4tm1Plev
involves: 129/Sv * C57BL/6
abnormal macrophage physiology J:170774
decreased IgG2a level J:170774
decreased interferon-gamma secretion J:170774
decreased interleukin-10 secretion J:170774
increased IgG1 level J:170774
increased interleukin-4 secretion J:170774
increased interleukin-6 secretion J:170774
increased interleukin-12 secretion J:170774
increased interleukin-13 secretion J:170774
increased susceptibility to parasitic infection J:170774
increased tumor necrosis factor secretion J:170774

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/19/2020
MGI 6.15
The Jackson Laboratory