Gprc6a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gprc6a
G protein-coupled receptor, family C, group 6, member A
MGI:2429498

33 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gprc6a^{tm1.1(KOMP)Vlcg}/Gprc6a⁺ C57BL/6N-Gprc6a^{tm1.1(KOMP)Vlcg}/Ucd	abnormal heart morphology	J:211773
	enlarged heart	J:211773
Gprc6a^{tm1.1(KOMP)Vlcg}/Gprc6a^{tm1.1(KOMP)Vlcg} C57BL/6N-Gprc6a^{tm1.1(KOMP)Vlcg}/Ucd	increased hemoglobin content	J:211773
	increased thymus weight	J:211773
Gprc6a^tm1.1Kry/Gprc6a^tm1.1Kry Tg(Cyp17a1-icre)AJako/0 involves: C57BL/6J	decreased epididymis weight	J:170888
	decreased seminal vesicle weight	J:170888
	decreased testis weight	J:170888
	increased male germ cell apoptosis	J:170888
	oligozoospermia	J:170888
	small testis	J:170888
Gprc6a^tm1Ldq/Gprc6a^tm1Ldq involves: 129X1/SvJ * C57BL/6	abnormal bone mineralization	J:144372
	abnormal circulating hormone level	J:144372
	abnormal circulating phosphate level	J:144372
	abnormal external male genitalia morphology	J:144372
	abnormal glucose homeostasis	J:144372
	abnormal glucose tolerance	J:144372
	abnormal internal male genitalia morphology	J:144372
	abnormal mammary gland development	J:144372
	abnormal urine homeostasis	J:144372
	decreased bone mineral density	J:144372
	decreased circulating insulin level	J:144372
	decreased circulating testosterone level	J:144372
	decreased lean body mass	J:144372
	decreased litter size	J:144372
	decreased seminal vesicle weight	J:144372
	decreased testis weight	J:144372
	hepatic steatosis	J:144372
	increased circulating estradiol level	J:144372
	increased circulating glucose level	J:144372
	increased insulin sensitivity	J:144372
	increased liver triglyceride level	J:144372
	increased urine beta2-microglobulin level	J:144372
	increased urine calcium level	J:144372
	increased urine phosphate level	J:144372
	increased white adipose tissue amount	J:144372
	small testis	J:144372

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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