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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hkdc1
hexokinase domain containing 1
MGI:2384910
16 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Hkdc1em1(IMPC)Bay/Hkdc1em1(IMPC)Bay
C57BL/6N-Hkdc1em1(IMPC)Bay/BayMmucd 		decreased bone mineral content J:211773
decreased bone mineral density J:211773
decreased lean body mass J:211773
increased total body fat amount J:211773
Hkdc1em1Xjz/Hkdc1em1Xjz
C57BL/6J-Hkdc1em1Xjz 		abnormal retina photoreceptor layer morphology J:266978
decreased a-wave amplitude J:266978
decreased b-wave amplitude J:266978
retina outer nuclear layer degeneration J:266978
thin retina inner nuclear layer J:266978
thin retina outer nuclear layer J:266978
normal vision/eye phenotype J:266978
Hkdc1em1Xjz/Hkdc1em2Xjz
C57BL/6J-Hkdc1em1Xjz Hkdc1em2Xjz 		abnormal retina photoreceptor layer morphology J:266978
decreased a-wave amplitude J:266978
decreased b-wave amplitude J:266978
retina outer nuclear layer degeneration J:266978
thin retina inner nuclear layer J:266978
thin retina outer nuclear layer J:266978
normal vision/eye phenotype J:266978
Hkdc1em2Xjz/Hkdc1em2Xjz
C57BL/6J-Hkdc1em2Xjz 		abnormal retina photoreceptor layer morphology J:266978
decreased a-wave amplitude J:266978
decreased b-wave amplitude J:266978
retina outer nuclear layer degeneration J:266978
thin retina inner nuclear layer J:266978
thin retina outer nuclear layer J:266978
normal vision/eye phenotype J:266978
Hkdc1tm1a(KOMP)Wtsi/Hkdc1+
involves: C57BL/6N 		decreased cellular glucose uptake J:240354
decreased liver triglyceride level J:240354
normal homeostasis/metabolism phenotype J:240354
impaired glucose tolerance J:240354
Hkdc1tm1a(KOMP)Wtsi/Hkdc1tm1a(KOMP)Wtsi
involves: C57BL/6N 		preweaning lethality, complete penetrance J:240354
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory