Slc39a14 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc39a14
solute carrier family 39 (zinc transporter), member 14
MGI:2384851

45 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gt(ROSA)26Sor^{tm1(CAG-Slc39a14*L438R)Wvh}/Gt(ROSA)26Sor⁺ Tg(Ctsk-cre)1Rda/0 involves: C57BL/6	abnormal compact bone morphology	J:261326
	abnormal tibia morphology	J:261326
	normal craniofacial phenotype	J:261326
	decreased bone ossification	J:261326
	decreased bone trabecular spacing	J:261326
	increased bone mineralization	J:261326
	increased bone trabecula number	J:261326
	increased trabecular bone thickness	J:261326
	increased trabecular bone volume	J:261326
Gt(ROSA)26Sor^{tm1(CAG-Slc39a14*L438R)Wvh}/Gt(ROSA)26Sor⁺ Tg(Runx2-icre)1Jtuc/0 involves: FVB/N	abnormal compact bone morphology	J:261326
	abnormal osteoblast physiology	J:261326
	normal craniofacial phenotype	J:261326
	decreased bone mineralization	J:261326
	decreased bone trabecula number	J:261326
	decreased diameter of femur	J:261326
	decreased diameter of tibia	J:261326
	decreased femur stiffness	J:261326
	decreased trabecular bone connectivity density	J:261326
	decreased trabecular bone mass	J:261326
	decreased trabecular bone volume	J:261326
	fragile skeleton	J:261326
	increased bone mineralization	J:261326
	increased bone ossification	J:261326
	increased bone trabecular spacing	J:261326
	increased femur compact bone thickness	J:261326
	increased osteoclast cell number	J:261326
Slc39a14^{tm1b(NCOM)Mfgc}/Slc39a14^{tm1b(NCOM)Mfgc} C57BL/6N-Slc39a14^{tm1b(NCOM)Mfgc}/Tcp	preweaning lethality, incomplete penetrance	J:211773
Slc39a14^tm1Lex/Slc39a14^tm1Lex B6;129S5-Slc39a14^tm1Lex/Mmucd	normal skeleton phenotype	J:261326
Slc39a14^tm1Lex/Slc39a14^tm1Lex involves: 129S5/SvEvBrd * C57BL/6J	abnormal liver zinc level	J:236296
	decreased hepatocyte proliferation	J:236296
	decreased liver weight	J:236296
	impaired liver regeneration	J:236296
	increased circulating alanine transaminase level	J:236296
Slc39a14^tm1Thir/Slc39a14^tm1Thir involves: 129 * C57BL/6	abnormal chondrocyte differentiation	J:171670
	abnormal gluconeogenesis	J:171670
	abnormal growth hormone level	J:171670
	abnormal liver zinc level	J:171670
	decreased body size	J:171670
	decreased body weight	J:171670
	decreased bone mineral density	J:171670
	decreased bone trabecula number	J:171670
	decreased bone volume	J:171670
	decreased circulating insulin-like growth factor I level	J:171670
	decreased length of long bones	J:171670
	increased bone trabecular spacing	J:171670
	osteoporosis	J:171670
	postnatal growth retardation	J:171670
	scoliosis	J:171670
	short femur	J:171670
	short tibia	J:171670
	torticollis	J:171670

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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