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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Mchr1
melanin-concentrating hormone receptor 1
MGI:2180756
36 phenotypes from 8 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Mchr1M1Btlr/Mchr1M1Btlr
C57BL/6J-Mchr1M1Btlr
decreased body weight J:272868
Mchr1tm1.1Blak/Mchr1tm1.1Blak
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * FVB/N
abnormal frequency of paradoxical sleep J:133199
abnormal sleep pattern J:133199
impaired behavioral response to xenobiotic J:133199
Mchr1tm1Blak/Mchr1tm1Blak
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
abnormal nervous system electrophysiology J:101206
abnormal passive avoidance behavior J:101206
decreased susceptibility to diet-induced obesity J:101206
Mchr1tm1Dgam/Mchr1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
decreased body weight J:95740
Mchr1tm1Dgam/Mchr1tm1Dgam
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal circadian temperature homeostasis J:95740
abnormal energy expenditure J:95740
decreased body weight J:95740
decreased susceptibility to diet-induced obesity J:95740
decreased total body fat amount J:95740
increased heart rate J:95740
increased locomotor activity J:95740
polyphagia J:95740
Mchr1tm1Lex/Mchr1tm1Lex
involves: 129S5/SvEvBrd * C57BL/6J
abnormal social investigation J:136869
decreased anxiety-related response J:136869
decreased percent body fat/body weight J:185494
decreased response to stress-induced hyperthermia J:136869
decreased serotonin level J:136869
increased body temperature J:136869
Mchr1tm1Ohl/Mchr1tm1Ohl
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
decreased compact bone mass J:90102
decreased compact bone thickness J:90102
increased circulating type I collagen C-terminal telopeptide level J:90102
osteoporosis J:90102
Mchr1tm1Sqn/Mchr1tm1Sqn
involves: 129S7/SvEvBrd * C57BL/6
abnormal hormone level J:81787
abnormal metabolism J:81787
decreased circulating leptin level J:81787
decreased percent body fat/body weight J:81787
decreased respiratory quotient J:81787
decreased susceptibility to diet-induced obesity J:81787
decreased thyroxine level J:81787
normal homeostasis/metabolism phenotype J:81787
increased circulating corticosterone level J:81787
increased fluid intake J:81787
increased lean body mass J:81787
increased locomotor activity J:81787
polyphagia J:81787
Mchr1tm1Yush/Mchr1tm1Yush
involves: 129 * C57BL/6
abnormal energy expenditure J:106819
decreased circulating insulin level J:106819
decreased circulating leptin level J:106819
decreased susceptibility to diet-induced obesity J:106819
decreased total body fat amount J:106819
increased food intake J:106819
slow postnatal weight gain J:106819
weight loss J:106819

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory