Plaat3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plaat3
phospholipase A and acyltransferase 3
MGI:2179715

34 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Plaat3^em1(IMPC)Tcp/Plaat3^em1(IMPC)Tcp C57BL/6NCrl-Plaat3^em1(IMPC)Tcp/Tcp	abnormal spleen morphology	J:211773
	impaired glucose tolerance	J:211773
	increased heart weight	J:211773
	increased mean corpuscular hemoglobin	J:211773
Plaat3^tm1.1Hsul/Plaat3^tm1.1Hsul B6.129P2-Pla2g16^tm1.1Hsul	abnormal glucose homeostasis	J:239202
	abnormal glycogen homeostasis	J:239202
	abnormal lipid metabolism	J:239202
	normal adipose tissue phenotype	J:239202
	decreased cellular glucose uptake	J:239202
	decreased circulating adiponectin level	J:239202
	decreased circulating free fatty acids level	J:239202
	decreased circulating leptin level	J:239202
	decreased circulating triglyceride level	J:239202
	decreased epididymal fat pad weight	J:239202
	decreased inguinal fat pad weight	J:239202
	decreased liver triglyceride level	J:239202
	decreased phospholipase A2 level	J:239202
	decreased renal fat pad weight	J:239202
	decreased susceptibility to diet-induced obesity	J:239202
	decreased susceptibility to weight gain	J:239202
	decreased triglyceride level	J:239202
	decreased white fat cell size	J:239202
	enhanced lipolysis	J:239202
	enlarged liver	J:239202
	hepatic steatosis	J:239202
	increased circulating alanine transaminase level	J:239202
	increased circulating glucose level	J:239202
	increased circulating insulin level	J:239202
	increased fasting circulating glucose level	J:239202
	increased fatty acid oxidation	J:239202
	increased lean body mass	J:239202
	increased oxygen consumption	J:239202
	insulin resistance	J:239202
	pale liver	J:239202

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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