Myh7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Myh7
myosin, heavy polypeptide 7, cardiac muscle, beta
MGI:2155600

17 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Myh7^em1Dsr/Myh7⁺ involves: C57BL/6J	no abnormal phenotype detected	J:277399
Myh7^em1Dsr/Myh7^em1Dsr involves: C57BL/6J	congestive heart failure	J:277399
Myh7^em1Dsr/Myh7^em1Dsr involves: C57BL/6J	embryonic lethality during organogenesis, complete penetrance	J:277399
Tg(Myh6-Myh7)102Rbns/? involves: FVB/N	abnormal cardiovascular system physiology	J:119670
Tg(Myh6-Myh7)102Rbns/? involves: FVB/N	abnormal myocardial fiber physiology	J:128692
Tg(Myh6-Myh7)102Rbns/Tg(Myh6-Myh7)102Rbns involves: FVB/N	abnormal heart atrium morphology	J:166125
	abnormal heart left ventricle morphology	J:166125
	abnormal physiological response to xenobiotic	J:166125
	abnormal response to cardiac infarction	J:166125
	normal cardiovascular system phenotype	J:166125
	decreased cardiac muscle contractility	J:166125
	decreased left ventricle systolic pressure	J:166125
	decreased systemic arterial systolic blood pressure	J:166125
	increased heart left ventricle weight	J:166125
	increased heart right ventricle weight	J:166125
	increased lung weight	J:166125
Tg(Myh6-Myh7)137Rbns/0 involves: FVB/N	abnormal heart atrium morphology	J:166125
	abnormal heart left ventricle morphology	J:166125
	abnormal physiological response to xenobiotic	J:166125
	abnormal response to cardiac infarction	J:166125
	decreased cardiac muscle contractility	J:166125
	decreased left ventricle systolic pressure	J:166125
	decreased systemic arterial systolic blood pressure	J:166125
	increased heart left atrium size	J:166125
	increased heart left ventricle weight	J:166125
	increased heart right ventricle weight	J:166125
	increased lung weight	J:166125

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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