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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Scrib
scribbled planar cell polarity
MGI:2145950
65 phenotypes from 10 alleles in 14 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
ScribCrc/Scrib+
C3H.Cg-ScribCrc
normal nervous system phenotype J:216413
ScribCrc/Scrib+
involves: BALB/c * C57BL/6 * NMRI
curly tail J:62635
kinked tail J:62635
ScribCrc/Scrib+
involves: C57BL/6J * NMRI
curly tail J:77245
ScribCrc/ScribCrc
C3H.Cg-ScribCrc
craniorachischisis J:216413
open neural tube J:216413
ScribCrc/ScribCrc
involves: BALB/c * C57BL/6 * CBA/CaJ * NMRI
craniorachischisis J:72608
ScribCrc/ScribCrc
involves: BALB/c * C57BL/6 * NMRI
abnormal forebrain development J:62635
abnormal lateral ventricle morphology J:62635
abnormal optic chiasm morphology J:62635
abnormal optic nerve innervation J:62635
abnormal retina morphology J:62635
abnormal retinal ganglion layer morphology J:62635
absent eyelids J:62635
absent third ventricle J:62635
craniorachischisis J:62635
decreased embryo size J:62635
decreased embryo weight J:62635
delayed embryo turning J:62635
encephalomeningocele J:62635
herniated abdominal wall J:62635
increased total retina thickness J:62635
microphthalmia J:62635
perinatal lethality, complete penetrance J:62635
ScribCrc/ScribCrc
involves: C3H/HeH * C57BL/6 * C57BL/6J * NMRI
craniorachischisis J:216413
ScribCrc/ScribCrc
involves: C57BL/6J * NMRI
craniorachischisis J:77245
decreased fetal size J:77245
delayed embryo turning J:77245
herniated abdominal wall J:77245
perinatal lethality, complete penetrance J:77245
Scribcrn2/Scribcrn2
involves: A/J * FVB/N
abnormal cochlea morphology J:174027
abnormal orientation of cochlear hair cell stereociliary bundles J:174027
exencephaly J:174027
kinked tail J:174027
open neural tube J:174027
Scribm90Asp/Scribm90Asp
Tg(mI56i-lacZ)1Mekk/0
involves: C57BL/6J * FVB/N
abnormal cerebral cortex morphology J:136795
abnormal embryonic neuroepithelium morphology J:136795
open neural tube J:136795
Scribm51206BHubr/Scribm51206BHubr
involves: C57BL/6 * FVB/N
abnormal cochlear inner hair cell morphology J:158680
abnormal lung lobe morphology J:173681
abnormal organ of Corti morphology J:158680
craniorachischisis J:158680, J:173681
herniated abdominal wall J:158680
small lung J:173681
Scribtm1.1Cj/Scribtm1.1Cj
Tg(Pax6-cre,GFP)1Pgr/0
involves: 129S1/Sv * FVB/N
abnormal corneal epithelium morphology J:204591
abnormal lens epithelium morphology J:204591
abnormal lens morphology J:204591
cataract J:204591
iris hyperplasia J:204591
small lens J:204591
Scribtm1.1Geno/Scribtm1.1Geno
Tg(NPHS2-cre)295Lbh/0
involves: 129S1/SvImJ * C57BL/6 * SJL
normal renal/urinary system phenotype J:190169
Scribtm1.1Phum/Scribtm1.1Phum
Tg(Pbsn-cre)20Fwan/0
involves: FVB/NCrl
abnormal prostate gland physiology J:178461
increased prostate intraepithelial neoplasia incidence J:178461
prostate gland hyperplasia J:178461
Scribtm1.2Geno/Scribtm1.2Geno
involves: 129S1/SvImJ * C57BL/6J
embryonic lethality during organogenesis, incomplete penetrance J:190169
lethality throughout fetal growth and development, incomplete penetrance J:190169
normal renal/urinary system phenotype J:190169
Scribtm1.2Phum/Scrib+
involves: FVB/N
abnormal pancreas morphology J:178461
abnormal prostate gland physiology J:178461
increased lung adenocarcinoma incidence J:178461
increased lung adenoma incidence J:216266
increased lung non-small cell carcinoma incidence J:216266
increased prostate gland weight J:178461
prostate gland hyperplasia J:178461
Scribtm1.2Phum/Scribtm1.2Phum
involves: FVB/N
abnormal gonad rudiment morphology J:178461
abnormal reproductive system development J:178461
craniorachischisis J:178461
curly tail J:178461
eyelids open at birth J:178461
herniated abdominal wall J:178461
perinatal lethality, complete penetrance J:178461
Scribtm1b(NCOM)Mfgc/Scrib+
C57BL/6N-Scribtm1a(NCOM)Mfgc/Tcp
decreased lean body mass J:211773
short tibia J:211773
Scribtm1b(NCOM)Mfgc/Scribtm1b(NCOM)Mfgc
C57BL/6N-Scribtm1a(NCOM)Mfgc/Tcp
abnormal craniofacial morphology J:211773
abnormal embryo size J:211773
abnormal eye morphology J:211773
abnormal hindbrain morphology J:211773
abnormal midbrain morphology J:211773
abnormal neural tube closure J:211773
abnormal pericardium morphology J:211773
abnormal placenta size J:211773
embryonic growth retardation J:211773
pale yolk sac J:211773
prenatal lethality prior to heart atrial septation J:211773
preweaning lethality, complete penetrance J:211773

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory