Ttll3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ttll3
tubulin tyrosine ligase-like family, member 3
MGI:2141418

11 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ttll3^{tm1a(EUCOMM)Wtsi}/Ttll3^{tm1a(EUCOMM)Wtsi} B6JTyr;B6N-Ttll3^{tm1a(EUCOMM)Wtsi}/Wtsi	decreased circulating potassium level	J:165965
Ttll3^{tm1a(EUCOMM)Wtsi}/Ttll3^{tm1a(EUCOMM)Wtsi} involves: C57BL/6 * C57BL/6N	no abnormal phenotype detected	J:213427
Ttll3^{tm1a(EUCOMM)Wtsi}/Ttll3^{tm1a(EUCOMM)Wtsi} involves: C57BL/6N	abnormal colon morphology	J:216383
	abnormal crypts of Lieberkuhn morphology	J:216383
	abnormal intestinal epithelium morphology	J:216383
	abnormal intestine physiology	J:216383
	increased incidence of tumors by chemical induction	J:216383
Ttll3^{tm1d(EUCOMM)Wtsi}/Ttll3^{tm1d(EUCOMM)Wtsi} involves: C57BL/6N	abnormal photoreceptor connecting cilium morphology	J:249732
	abnormal retina outer nuclear layer morphology	J:249732
	retina outer nuclear layer degeneration	J:249732
	retina photoreceptor degeneration	J:249732

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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