Depdc5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Depdc5
DEP domain containing 5
MGI:2141101

19 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Depdc5^{tm1b(EUCOMM)Hmgu}/Depdc5⁺ C57BL/6N-Depdc5^{tm1b(EUCOMM)Hmgu}/H	impaired glucose tolerance	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased total body fat amount	J:211773
Depdc5^{tm1b(EUCOMM)Hmgu}/Depdc5^{tm1b(EUCOMM)Hmgu} C57BL/6N-Depdc5^{tm1b(EUCOMM)Hmgu}/H	preweaning lethality, complete penetrance	J:211773
Depdc5^{tm1c(EUCOMM)Hmgu}/Depdc5⁺ Tg(Syn1-cre)671Jxm/0 involves: C57BL/6N * CBA	decreased body weight	J:260943
Depdc5^{tm1c(EUCOMM)Hmgu}/Depdc5^{tm1c(EUCOMM)Hmgu} Tg(Syn1-cre)671Jxm/0 involves: C57BL/6N * CBA	abnormal dendrite morphology	J:260943
	astrocytosis	J:260943
	normal behavior/neurological phenotype	J:260943
	decreased body weight	J:260943
	decreased susceptibility to xenobiotic induced morbidity/mortality	J:260943
	increased brain size	J:260943
	increased compact bone thickness	J:260943
	increased susceptibility to pharmacologically induced seizures	J:260943
	limb grasping	J:260943
	megacephaly	J:260943
	neuron hypertrophy	J:260943
	premature death	J:260943
	seizures	J:260943
	tonic seizures	J:260943
	tonic-clonic seizures	J:260943

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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