32 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hspb8em1(IMPC)J/Hspb8em1(IMPC)J C57BL/6NJ-Hspb8em1(IMPC)J/Mmjax	abnormal coat/ hair morphology	J:211773
	decreased leukocyte cell number	J:211773
	hyperactivity	J:211773
	increased circulating phosphate level	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Hspb8tm1.1Depr/Hspb8tm1.1Depr B.129-Hspb8tm1.1Depr	abnormal cardiovascular system physiology	J:186292
	abnormal cellular respiration	J:186292
	abnormal heart morphology	J:186292
	abnormal myocardium layer morphology	J:186292
	cardiac hypertrophy	J:186292
	decreased circulating interleukin-6 level	J:186292
	decreased ventricle muscle contractility	J:186292
	increased heart left ventricle size	J:186292
	increased left ventricle diastolic pressure	J:186292
	increased lung weight	J:186292
	increased susceptibility to induced morbidity/mortality	J:186292
	thick interventricular septum	J:186292
Hspb8tm1.1Vti/Hspb8tm1.1Vti involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl	abnormal skeletal muscle morphology	J:284796
	normal behavior/neurological phenotype	J:284796
	normal nervous system phenotype	J:284796
Hspb8tm1Vti/Hspb8+ involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl	abnormal muscle fiber morphology	J:284796
	abnormal sciatic nerve morphology	J:284796
	abnormal Z line morphology	J:284796
	normal behavior/neurological phenotype	J:284796
Hspb8tm1Vti/Hspb8tm1Vti involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl	abnormal action potential	J:284796
	abnormal sciatic nerve morphology	J:284796
	abnormal skeletal muscle fiber morphology	J:284796
	abnormal Z line morphology	J:284796
	axon degeneration	J:284796
	decreased grip strength	J:284796
	impaired autophagy	J:284796
	impaired coordination	J:284796
	muscular atrophy	J:284796
	myopathy	J:284796
	skeletal muscle fiber degeneration	J:284796