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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Alms1
ALMS1, centrosome and basal body associated
MGI:1934606
55 phenotypes from 12 alleles in 12 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Alms1bbb/Alms1bbb
C57BL/6JSfdAnu-Alms1bbb/Anu
abnormal eye physiology J:104190
hyperglycemia J:104190
impaired hearing J:104190
increased circulating insulin level J:104190
obese J:104190
small gonad J:104190
Alms1foz/Alms1foz
involves: NOD
abnormal hepatocyte morphology J:107058
enlarged liver J:107058
hepatic steatosis J:107058
hyperglycemia J:107058
increased circulating insulin level J:107058
increased food intake J:107058
increased liver weight J:107058
insulin resistance J:107058
liver fibrosis J:107058
Alms1Gt(XH152)Byg/Alms1Gt(XH152)Byg
involves: 129P2/OlaHsd * C57BL/6J
abnormal eye electrophysiology J:100403
abnormal retina outer nuclear layer morphology J:100403
abnormal seminiferous tubule morphology J:100403
albuminuria J:100403
normal cellular phenotype J:100403
crystalluria J:100403
degranulated pancreatic beta cells J:100403
dilated proximal convoluted tubule J:100403
enlarged kidney J:100403
hyperglycemia J:100403
increased body weight J:100403
increased circulating cholesterol level J:100403
increased circulating insulin level J:100403
increased kidney weight J:100403
increased liver weight J:100403
increased or absent threshold for auditory brainstem response J:100403
increased white adipose tissue amount J:100403
macrovesicular hepatic steatosis J:100403
microvesicular hepatic steatosis J:100403
obese J:100403
pancreatic islet hyperplasia J:100403
small gonad J:100403
tubulointerstitial nephritis J:100403
Alms1L2131X/Alms1L2131X
involves: C57BL/6 * NOD
abnormal circulating cholesterol level J:118221
abnormal eye physiology J:118221
abnormal proximal convoluted tubule morphology J:118221
abnormal renal tubule epithelial cell primary cilium morphology J:118221
abnormal spermatogenesis J:118221
dilated renal tubule J:118221
hepatic steatosis J:118221
increased circulating HDL cholesterol level J:118221
increased circulating insulin level J:118221
increased circulating leptin level J:118221
increased circulating triglyceride level J:118221
increased fat cell size J:118221
increased kidney apoptosis J:118221
increased kidney cell proliferation J:118221
increased susceptibility to weight gain J:118221
increased total body fat amount J:118221
increased urine protein level J:118221
seminiferous tubule degeneration J:118221
Alms1m1Btlr/Alms1m1Btlr
C57BL/6J-Alms1m1Btlr
increased body weight J:218964
Alms1m2Btlr/Alms1m2Btlr
C57BL/6J-Alms1m2Btlr
impaired glucose tolerance J:264648
Alms1m3Btlr/Alms1m3Btlr
C57BL/6J-Alms1m3Btlr
impaired glucose tolerance J:264649
increased body size J:264649
increased body weight J:264649
increased circulating insulin level J:264649
increased fasting circulating glucose level J:264649
Alms1m4Btlr/Alms1m4Btlr
C57BL/6J-Alms1m4Btlr
increased body weight J:267551
Alms1m5Btlr/Alms1m5Btlr
C57BL/6J-Alms1m5Btlr
increased body weight J:267682
Alms1m6Btlr/Alms1m6Btlr
C57BL/6J-Alms1m6Btlr
increased body weight J:274969
Alms1tm1b(EUCOMM)Hmgu/Alms1tm1b(EUCOMM)Hmgu
C57BL/6N-Alms1tm1b(EUCOMM)Hmgu/H
abnormal locomotor behavior J:211773
increased circulating amylase level J:211773
Alms1tvrm102/Alms1Gt(XH152)Byg
involves: 129P2/OlaHsd * C57BL/6J
obese J:243745
retina photoreceptor degeneration J:243745
Alms1tvrm102/Alms1tvrm102
C57BL/6J-Alms1tvrm102/Pjn
increased susceptibility to age-related retinal degeneration J:243745
obese J:243745
retina outer nuclear layer degeneration J:243745
retina photoreceptor degeneration J:243745
retina pigment epithelium atrophy J:243745

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory