Egln3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Egln3
egl-9 family hypoxia-inducible factor 3
MGI:1932288

24 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Egln3^{tm1b(EUCOMM)Wtsi}/Egln3^{tm1b(EUCOMM)Wtsi} C57BL/6N-Egln3^{tm1b(EUCOMM)Wtsi}/Bay	abnormal sinus arrhythmia	J:211773
Egln3^tm1Fong/Egln3^tm1Fong involves: 129S6/SvEvTac * C57BL/6	normal cardiovascular system phenotype	J:133568
	normal hematopoietic system phenotype	J:132720
	normal muscle phenotype	J:132630
Egln3^tm1Fong/Egln3^tm1Fong involves: 129S6/SvEvTac * C57BL/6 * CD-1 * FVB/N	normal cardiovascular system phenotype	J:114669
	normal embryo phenotype	J:114669
Egln3^tm1Jomy/Egln3^tm1Jomy Not Specified	no abnormal phenotype detected	J:213191
Egln3^tm1Pjr/Egln3^tm1Pjr involves: 129S/SvEv * Swiss	abnormal adrenal chromaffin cell morphology	J:136034
	abnormal adrenal gland secretion	J:136034
	abnormal adrenal medulla morphology	J:136034
	abnormal axon morphology	J:136034
	abnormal carotid body morphology	J:136034
	abnormal innervation	J:136034
	abnormal nervous system development	J:136034
	abnormal neuron morphology	J:136034
	abnormal neuron physiology	J:136034
	abnormal physiological response to xenobiotic	J:136034
	abnormal pupil morphology	J:136034
	decreased circulating adrenaline level	J:136034
	decreased circulating noradrenaline level	J:136034
	decreased neuron apoptosis	J:136034
	decreased survivor rate	J:136034
	decreased systemic arterial blood pressure	J:136034
	decreased systemic arterial systolic blood pressure	J:136034
	enlarged superior cervical ganglion	J:136034

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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