Ralgapa1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ralgapa1
Ral GTPase activating protein, alpha subunit 1
MGI:1931050

18 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ralgapa1^em1(IMPC)J/Ralgapa1⁺ C57BL/6NJ-Ralgapa1^em1(IMPC)J/Mmjax	hyperactivity	J:211773
Ralgapa1^em1(IMPC)J/Ralgapa1^em1(IMPC)J C57BL/6NJ-Ralgapa1^em1(IMPC)J/Mmjax	preweaning lethality, complete penetrance	J:211773
Ralgapa1^tm1.1Schen/Ralgapa1^tm1.1Schen involves: C57BL/6J	abnormal muscle physiology	J:287672
	decreased muscle cell glucose uptake	J:287672
	increased body weight	J:287672
	increased circulating cholesterol level	J:287672
	increased circulating free fatty acids level	J:287672
	increased circulating insulin level	J:287672
	increased circulating triglyceride level	J:287672
	increased fasting circulating glucose level	J:287672
	increased fat cell size	J:287672
	increased liver cholesterol level	J:287672
	increased liver triglyceride level	J:287672
	increased total body fat amount	J:287672
	insulin resistance	J:287672
Ralgapa1^{tm2c(KOMP)Wtsi}/Ralgapa1^{tm2c(KOMP)Wtsi} Myl1^tm1(cre)Sjb/Myl1⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * C57BL/6N	abnormal lipid homeostasis	J:287672
	improved glucose tolerance	J:287672
	increased circulating cholesterol level	J:287672
	increased circulating free fatty acids level	J:287672
	increased circulating insulin level	J:287672
	increased circulating triglyceride level	J:287672
	increased muscle cell glucose uptake	J:287672

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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