Prss8 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prss8
serine protease 8 (prostasin)
MGI:1923810

27 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
F2rl1^tm1Cgh/F2rl1^tm1Cgh Tg(KRT14-Prss8)2Hum/? involves: 129S4/SvJae * C57BL/6 * DBA/2	normal integument phenotype	J:189278
Oat^rhg/Prss8^fr involves: AKR/J * C57BL/6JEi * FS/EiJ	no abnormal phenotype detected	J:213842
Prss8^em1Bug/Prss8^em1Bug Spint2^{Gt(KST272)Byg}/Spint2^{Gt(KST272)Byg} involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * FVB/NJ * NIH Black Swiss	abnormal digestive system morphology	J:261068
	abnormal enterocyte proliferation	J:261068
	abnormal intestinal epithelium morphology	J:261068
	abnormal intestinal goblet cell morphology	J:261068
	abnormal intestine morphology	J:261068
	abnormal large intestine crypts of Lieberkuhn morphology	J:261068
	abnormal large intestine morphology	J:261068
	abnormal small intestine morphology	J:261068
	decreased birth weight	J:261068
	decreased colon goblet cell number	J:261068
	decreased intestine length	J:261068
	intestinal hemorrhage	J:261068
	postnatal growth retardation	J:261068
	postnatal lethality, complete penetrance	J:261068
	small intestinal villus atrophy	J:261068
Prss8^fr/Prss8⁺ Spint2^{Gt(KST272)Byg}/Spint2^{Gt(KST272)Byg} involves: 129P2/OlaHsd * DBA	embryonic lethality, complete penetrance	J:188121
Prss8^fr/Prss8⁺ Spint1^tm1Bug/Spint1^tm1Bug involves: 129S6/SvEvTac * DBA	abnormal placenta morphology	J:188121
	curly tail	J:188121
	embryonic lethality during organogenesis, complete penetrance	J:188121
	exencephaly	J:188121
	spina bifida	J:188121
Prss8^fr/Prss8^fr Spint1^tm1Bug/Spint1^tm1Bug involves: 129S6/SvEvTac * DBA	abnormal coat appearance	J:188121
	normal embryo phenotype	J:188121
	prenatal lethality, incomplete penetrance	J:188121
Prss8^fr/Prss8^fr Spint2^{Gt(KST272)Byg}/Spint2^{Gt(KST272)Byg} involves: 129P2/OlaHsd * DBA	normal embryo phenotype	J:188121
	exencephaly	J:188121
	prenatal lethality, incomplete penetrance	J:188121
Prss8^fr/Prss8^fr Spint2^{Gt(KST272)Byg}/Spint2^{Gt(KST272)Byg} St14^tm1Bug/St14⁺ involves: 129P2/OlaHsd * DBA	normal embryo phenotype	J:188121
	normal mortality/aging	J:188121

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