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Oatrhg
Spontaneous Allele Detail
Summary
Symbol: Oatrhg
Name: ornithine aminotransferase; retarded hair growth
MGI ID: MGI:1857018
Gene: Oat  Location: Chr7:132159207-132178127 bp, - strand  Genetic Position: Chr7, 76.3 cM
Alliance: Oatrhg page
Small size and retarded hair growth in Oatrhg/Oatrhg mice

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  AKR/J
Mutation
description
Allele Type:    Spontaneous (Humanized sequence, Hypomorph)
Mutation:    Single point mutation
 
Mutation detailsA spontaneous G-to-C transversion in exon 9 causes a glycine to alanine substitution at amino acid 353 (p.G353A), an evolutionarily conserved residue. This glycine is mutated in at least one family with gyrate atrophy of the choroid and retina. (J:213842, J:222308)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 8 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Oat Mutation:  18 strains or lines available
References
Original:  J:13745 Fox S, et al., Retarded hair growth (rhg). Mouse News Lett. 1978;58:47
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory