Gpsm2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gpsm2
G-protein signalling modulator 2 (AGS3-like, C. elegans)
MGI:1923373

21 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gpsm2^tm1.2Fuma/Gpsm2^tm1.2Fuma involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj	abnormal cell differentiation	J:132370
	abnormal inner hair cell stereociliary bundle morphology	J:230725
	abnormal neuron specification	J:132370
	abnormal orientation of outer hair cell stereociliary bundles	J:230725
	abnormal outer hair cell stereociliary bundle morphology	J:230725
	absent pinna reflex	J:230725
	absent startle reflex	J:230725
	deafness	J:230725
	increased or absent threshold for auditory brainstem response	J:230725
	normal nervous system phenotype	J:132370, J:230725
	short inner hair cell stereocilia	J:230725
Gpsm2^{tm1a(EUCOMM)Wtsi}/Gpsm2^{tm1a(EUCOMM)Wtsi} C57BL/6-Gpsm2^{tm1a(EUCOMM)Wtsi}	abnormal cell cytoskeleton morphology	J:214064
	abnormal cochlear hair cell morphology	J:214064
	abnormal cochlear hair cell stereociliary bundle morphology	J:214064, J:236519
	abnormal kinocilium morphology	J:214064
	deafness	J:236519
	increased or absent threshold for auditory brainstem response	J:236519
Gpsm2^{tm1b(EUCOMM)Wtsi}/Gpsm2⁺ C57BL/6N-Gpsm2^{tm1b(EUCOMM)Wtsi}/Ieg	abnormal lens morphology	J:211773
	abnormal retina morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	increased mean platelet volume	J:211773
Gpsm2^{tm1b(EUCOMM)Wtsi}/Gpsm2^{tm1b(EUCOMM)Wtsi} C57BL/6N-Gpsm2^{tm1b(EUCOMM)Wtsi}/Ieg	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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