Tbc1d10c Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tbc1d10c
TBC1 domain family, member 10c
MGI:1922072

9 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tbc1d10c^tm1.1Psou/Tbc1d10c^tm1.2Psou Cd79a^tm1(cre)Reth/Cd79a⁺ involves: 129S2/SvPas * BALB/c * C57BL/6J	abnormal B cell physiology	J:211913
	increased anti-double stranded DNA antibody level	J:211913
	increased IgG level	J:211913
	increased IgM level	J:211913
	increased susceptibility to systemic lupus erythematosus	J:211913
Tbc1d10c^tm1.1Psou/Tbc1d10c^tm1.2Psou Tg(Lck-cre)#Nik/0 involves: 129S2/SvPas * C57BL/6 * C57BL/6J * DBA/2	normal immune system phenotype	J:211913
Tbc1d10c^tm1.2Psou/Tbc1d10c^tm1.2Psou involves: 129S2/SvPas * C57BL/6J	abnormal B cell physiology	J:211913
	abnormal response to infection	J:211913
	abnormal T cell activation	J:211913
	normal immune system phenotype	J:211913
	increased anti-double stranded DNA antibody level	J:211913
	increased IgG level	J:211913
	increased susceptibility to systemic lupus erythematosus	J:211913
	increased T cell proliferation	J:211913

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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