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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
C2cd5
C2 calcium-dependent domain containing 5
MGI:1921991
32 phenotypes from 1 allele in 1 genetic background
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Allelic Composition
Genetic Background
Annotated Term Reference
C2cd5Gt(IST12020E4)Tigm/C2cd5Gt(IST12020E4)Tigm
C57BL/6N-C2cd5Gt(IST12020E4)Tigm
abnormal adrenal gland secretion J:284780
abnormal beige fat cell physiology J:284780
abnormal brown adipose tissue thermogenesis J:284780
abnormal glucose homeostasis J:284780
decreased adipocyte glucose uptake J:284780
decreased basal metabolism J:284780
decreased cardiac muscle cell glucose uptake J:284780
decreased circulating adrenaline level J:284780
decreased circulating free fatty acids level J:284780
decreased core body temperature J:284780
decreased energy expenditure J:284780
decreased fatty acid oxidation J:284780
decreased hepatic glucose production J:284780
decreased muscle cell glucose uptake J:284780
decreased oxygen consumption J:284780
decreased vertical activity J:284780
hepatic steatosis J:284780
impaired adaptive thermogenesis J:284780
impaired glucose tolerance J:284780
impaired lipolysis J:284780
increased adrenaline level J:284780
increased brown fat cell lipid droplet size J:284780
increased brown fat lipid droplet number J:284780
increased fasting circulating glucose level J:284780
increased lipogenesis J:284780
increased liver triglyceride level J:284780
increased noradrenaline level J:284780
increased susceptibility to age related obesity J:284780
increased susceptibility to diet-induced obesity J:284780
increased white fat cell size J:284780
insulin resistance J:284780
obese J:284780

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory