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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Clec16a
C-type lectin domain family 16, member A
MGI:1921624
30 phenotypes from 3 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Clec16acurt/Clec16acurt
SWR/J-Clec16acurt/GrsrJ
abnormal digit morphology J:172931
decreased body size J:172931
decreased body weight J:172931
impaired hearing J:172931
increased or absent threshold for auditory brainstem response J:172931
narrow eye opening J:172931
perinatal lethality, incomplete penetrance J:172931
premature death J:172931
preweaning lethality, incomplete penetrance J:172931
Purkinje cell degeneration J:251104
wavy tail J:172931
Clec16aem1(IMPC)J/Clec16a+
C57BL/6NJ-Clec16aem1(IMPC)J/Mmjax
increased exploration in new environment J:211773
Clec16aem1(IMPC)J/Clec16aem1(IMPC)J
C57BL/6NJ-Clec16aem1(IMPC)J/Mmjax
abnormal body wall morphology J:211773
abnormal embryo size J:211773
preweaning lethality, complete penetrance J:211773
Clec16atm1.1Hhak/Clec16atm1.1Hhak
involves: C57BL/6 * SJL
no abnormal phenotype detected J:214528
Clec16atm1.1Hhak/Clec16atm1.1Hhak
Ndor1Tg(UBC-cre/ERT2)1Ejb/0
involves: 129S/SvEv * C57BL/6 * SJL
abnormal mitophagy J:214528
decreased oxygen consumption J:214528
Clec16atm1.1Hhak/Clec16atm1.1Hhak
Tg(Pdx1-cre)1Herr/0
involves: C57BL/6 * C57BL/6J * CBA/J * SJL
abnormal endoplasmic reticulum morphology J:214528
abnormal mitochondrial morphology J:214528
abnormal mitophagy J:214528
abnormal pancreatic alpha cell morphology J:214528
abnormal pancreatic beta cell morphology J:214528
abnormal pancreatic beta cell physiology J:214528
decreased insulin secretion J:214528
decreased oxygen consumption J:214528
disorganized mitochondrial cristae J:214528
normal endocrine/exocrine gland phenotype J:214528
hyperglycemia J:214528
impaired glucose tolerance J:214528
increased mitochondrial size J:214528
Tg(CMV-GFP,-RNAi:Clec16a)KD3Kslr/0
NOD-Tg(CMV-GFP,-RNAi:Clec16a)KD3Kslr
increased physiological sensitivity to xenobiotic J:285312

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory