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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Vsir
V-set immunoregulatory receptor
MGI:1921298
12 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cd274tm1Igu/Cd274tm1Igu
Vsirtm1Lex/Vsirtm1Lex
involves: 129S5/SvEvBrd * C57BL/6 		abnormal T cell activation J:222944
Pdcd1tm1Hon/Pdcd1tm1Hon
Vsirtm1Lex/Vsirtm1Lex
involves: 129S2/SvPas * 129S5/SvEvBrd * C57BL/6 		abnormal T cell activation J:222944
hepatic necrosis J:222944
normal immune system phenotype J:222944
increased IgA level J:222944
increased IgM level J:222944
increased inflammatory response J:222944
increased interferon-gamma secretion J:222944
increased interleukin-17 secretion J:222944
increased tumor necrosis factor secretion J:222944
pancreas necrosis J:222944
pulmonary necrosis J:222944
Pdcd1tm1Hon/Pdcd1tm1Hon
Vsirtm1Lex/Vsirtm1Lex
Tg(Tcra2D2,Tcrb2D2)1Kuch/0
involves: 129S2/SvPas * 129S5/SvEvBrd * C57BL/6 		increased susceptibility to experimental autoimmune encephalomyelitis J:222944
Vsirtm1Lex/Vsirtm1Lex
Tg(Tcra2D2,Tcrb2D2)1Kuch/0
involves: 129S5/SvEvBrd * C57BL/6 		increased susceptibility to experimental autoimmune encephalomyelitis J:222944
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory