Lima1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lima1
LIM domain and actin binding 1
MGI:1920992

9 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lima1^tm1.1Blsg/Lima1⁺ involves: C57BL/6 * FVB/N	decreased circulating cholesterol level	J:263730
Lima1^tm1.1Blsg/Lima1⁺ involves: C57BL/6 * FVB/N	decreased intestinal cholesterol absorption	J:263730
Lima1^tm1.1Blsg/Lima1^tm1.1Blsg involves: C57BL/6 * FVB/N	decreased intestinal cholesterol absorption	J:263730
Lima1^{tm1b(KOMP)Wtsi}/Lima1^{tm1b(KOMP)Wtsi} C57BL/6N-Lima1^{tm1b(KOMP)Wtsi}/J	decreased thigmotaxis	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Lima1^tm1Blsg/Lima1⁺ Tg(Vil1-cre/ERT2)23Syr/0 involves: C57BL/6 * DBA/2	decreased intestinal cholesterol absorption	J:263730
Lima1^tm1Blsg/Lima1^tm1Blsg Tg(Vil1-cre/ERT2)23Syr/0 involves: C57BL/6 * DBA/2	decreased circulating cholesterol level	J:263730
	decreased circulating HDL cholesterol level	J:263730
	decreased circulating LDL cholesterol level	J:263730
	decreased circulating VLDL cholesterol level	J:263730
	decreased intestinal cholesterol absorption	J:263730
	decreased liver cholesterol level	J:263730
	normal homeostasis/metabolism phenotype	J:263730

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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