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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tubb2b
tubulin, beta 2B class IIB
MGI:1920960
26 phenotypes from 3 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Tubb2bbrdp/Tubb2b+
involves: A/J * CD-1 * FVB/N
normal reproductive system phenotype J:201099
Tubb2bbrdp/Tubb2b+
involves: A/J * FVB
abnormal brain interneuron morphology J:201099
abnormal cerebral cortex morphology J:201099
hyperactivity J:201099
reduced fertility J:201099
normal reproductive system phenotype J:201099
Tubb2bbrdp/Tubb2b+
involves: A/J * FVB/N * ICR
normal reproductive system phenotype J:201099
Tubb2bbrdp/Tubb2bbrdp
involves: A/J * FVB
abnormal basal ganglion morphology J:201099
abnormal brain internal capsule morphology J:201099
abnormal cerebral cortex morphology J:201099
abnormal choroid plexus morphology J:201099
abnormal cortical plate morphology J:201099
abnormal neuronal precursor proliferation J:201099
abnormal telencephalon morphology J:201099
absent anterior commissure J:201099
absent corpus callosum J:201099
decreased midbrain size J:201099
enlarged brain ventricles J:201099
increased neuron apoptosis J:201099
prenatal lethality, complete penetrance J:201099
respiratory distress J:201099
short snout J:201099
small cerebellum J:201099
small olfactory bulb J:201099
thin cerebral cortex J:201099
Tubb2bbrdp/Tubb2bbrdp
involves: A/J * FVB/N
abnormal telencephalon morphology J:174027
hydrocephaly J:174027
small olfactory bulb J:174027
Tubb2bem1(IMPC)J/Tubb2bem1(IMPC)J
C57BL/6NJ-Tubb2bem1(IMPC)J/Mmjax
preweaning lethality, incomplete penetrance J:211773
Tubb2bem1Rstot/Tubb2bem1Rstot
involves: C57BL/6J * C57BL/6N
abnormal cerebral cortex morphology J:278765
abnormal primary motor cortex morphology J:278765
abnormal somatosensory cortex morphology J:278765

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory