Slc17a7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc17a7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
MGI:1920211

29 phenotypes from 6 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc17a7^em1(IMPC)H/Slc17a7^em1(IMPC)H C57BL/6N-Slc17a7^em1(IMPC)H/H	preweaning lethality, incomplete penetrance	J:211773
Slc17a7^{tm1.1(cre)Hze}/Slc17a7⁺ involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCr	no abnormal phenotype detected	J:146821
Slc17a7^tm1.1Ehzg/Slc17a7^tm1.1Ehzg involves: 129P2/OlaHsd * C57BL/6 * FVB/N	normal nervous system phenotype	J:177266
Slc17a7^tm1Bros/Slc17a7⁺ involves: 129 * C57BL/6N	abnormal long-term object recognition memory	J:118618
	abnormal nervous system physiology	J:118618
	behavioral despair	J:118618
	increased anxiety-related response	J:118618
Slc17a7^tm1Bros/Slc17a7^tm1Bros involves: 129P2/OlaHsd	abnormal excitatory postsynaptic currents	J:89958
	abnormal miniature excitatory postsynaptic currents	J:89958
	decreased body weight	J:89958
	hunched posture	J:89958
	lethality at weaning, complete penetrance	J:89958
	postnatal growth retardation	J:89958
	unresponsive to tactile stimuli	J:89958
Slc17a7^tm1Edw/Slc17a7^tm1Edw involves: 129X1/SvJ	abnormal axon morphology	J:105647
	abnormal CNS synaptic transmission	J:105647
	abnormal excitatory postsynaptic potential	J:105647
	abnormal food intake	J:105647
	abnormal neurotransmitter uptake	J:105647
	abnormal single cell response	J:105647
	abnormal synaptic vesicle number	J:105647
	blindness	J:105647
	decreased miniature excitatory postsynaptic current frequency	J:105647
	impaired coordination	J:105647
	increased startle reflex	J:105647
	premature death	J:105647
Slc17a7^tm1Lex/Slc17a7⁺ involves: 129S5/SvEvBrd * C57BL/6J	abnormal excitatory postsynaptic potential	J:174414
	abnormal inhibitory learning	J:174414
	reduced long-term potentiation	J:174414
Slc17a7^tm1Lex/Slc17a7^tm1Lex involves: 129S5/SvEvBrd * C57BL/6J	decreased body size	J:103485
	postnatal growth retardation	J:174414
	premature death	J:103485, J:174414

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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