Amer1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Amer1
APC membrane recruitment 1
MGI:1919595

58 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Amer1^tm1.1Nbar/Y Tg(BGLAP-cre)1Clem/0 involves: 129S4/SvJae * C57BL/6 * FVB/NJ * SJL	normal skeleton phenotype	J:173242
Amer1^tm1.1Nbar/Y Tg(Col2a1-cre)1Bhr/0 involves: 129S4/SvJae * C57BL/6 * SJL	normal skeleton phenotype	J:173242
Amer1^tm1.1Nbar/Y Tg(Prrx1-cre)1Cjt/0 involves: 129S4/SvJae * C57BL/6 * SJL	abnormal appendicular skeleton morphology	J:173242
	abnormal bone structure	J:173242
	abnormal compact bone morphology	J:173242
	abnormal deltoid tuberosity morphology	J:173242
	abnormal fat cell differentiation	J:173242
	abnormal fat cell morphology	J:173242
	abnormal long bone morphology	J:173242
	abnormal osteoblast differentiation	J:173242
	abnormal sternum morphology	J:173242
	abnormal sternum ossification	J:173242
	abnormal trabecular bone morphology	J:173242
	delayed bone mineralization	J:173242
	increased bone mineralization	J:173242
	increased bone ossification	J:173242
	increased bone volume	J:173242
	increased osteoblast cell number	J:173242
	increased trabecular bone thickness	J:173242
	osteosclerosis	J:173242
Amer1^tm1.1Nbar/Y Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 involves: 129S4/SvJae * C57BL/6 * CD-1 * SJL	abnormal bone structure	J:173242
	abnormal skeleton development	J:173242
	delayed fontanelle closure	J:173242
	increased bone mineralization	J:173242
	increased bone ossification	J:173242
	increased bone volume	J:173242
	increased osteoblast cell number	J:173242
	increased trabecular bone thickness	J:173242
	large fontanelles	J:173242
	osteosclerosis	J:173242
Amer1^tm1.2Nbar/Y involves: 129S4/SvJae * C57BL/6 * CD-1 * SJL	abnormal bone mineralization	J:173242
	abnormal compact bone morphology	J:173242
	abnormal cranial suture morphology	J:173242
	abnormal deltoid tuberosity morphology	J:173242
	abnormal endochondral bone ossification	J:173242
	abnormal intramembranous bone ossification	J:173242
	abnormal kidney development	J:173242
	abnormal kidney morphology	J:173242
	abnormal long bone morphology	J:173242
	abnormal metanephric mesenchyme morphology	J:173242
	abnormal neurocranium morphology	J:173242
	abnormal skeleton morphology	J:173242
	abnormal sternum morphology	J:173242
	abnormal sternum ossification	J:173242
	abnormal ulna morphology	J:173242
	abnormal ureteric bud morphology	J:173242
	abnormal Wolffian duct morphology	J:173242
	absent deltoid tuberosity	J:173242
	absent kidney	J:173242
	bowed radius	J:173242
	bowed ulna	J:173242
	cyanosis	J:173242
	decreased brown adipose tissue amount	J:173242
	decreased total body fat amount	J:173242
	decreased white adipose tissue amount	J:173242
	delayed endochondral bone ossification	J:173242
	delayed intramembranous bone ossification	J:173242
	enlarged cranium	J:173242
	enlarged heart	J:173242
	enlarged kidney	J:173242
	enlarged neurocranium	J:173242
	increased cranium width	J:173242
	increased fetal size	J:173242
	increased fetal weight	J:173242
	increased heart weight	J:173242
	increased metanephric mesenchyme apoptosis	J:173242
	increased radius size	J:173242
	neonatal lethality, complete penetrance	J:173242
	osteosclerosis	J:173242
	single kidney	J:173242
	spleen hypoplasia	J:173242
Amer1^tm1.2Nbar/Amer1⁺ involves: 129S4/SvJae * C57BL/6 * CD-1 * SJL	increased bone mineral density	J:173242
	increased fetal size	J:173242
	increased fetal weight	J:173242

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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