Trmu Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Trmu
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
MGI:1919276

25 phenotypes from 2 alleles in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Trmu^tm1Tomik/Trmu^tm1Tomik involves: C57BL/6 * DBA	abnormal hepatocyte mitochondrial morphology	J:235644
	abnormal homeostasis	J:235644
	abnormal inflammatory response	J:235644
	abnormal mitochondrial crista morphology	J:235644
	abnormal mitochondrial physiology	J:235644
	abnormal nucleotide metabolism	J:235644
	abnormal tricarboxylic acid cycle	J:235644
	decreased circulating amylase level	J:235644
	decreased circulating calcium level	J:235644
	decreased circulating cholesterol level	J:235644
	decreased circulating creatinine level	J:235644
	decreased circulating HDL cholesterol level	J:235644
	decreased circulating serum albumin level	J:235644
	hepatic necrosis	J:235644
	normal homeostasis/metabolism phenotype	J:235644
	increased cell nucleus count	J:235644
	increased circulating alanine transaminase level	J:235644
	increased circulating aspartate transaminase level	J:235644
	increased circulating lactate dehydrogenase level	J:235644
	increased circulating lactate level	J:235644
	increased hepatocyte karyomegaly	J:235644
	increased mitochondrial DNA content	J:235644
	increased mitochondrial size	J:235644
Trmu^tm1.1Tomik/Trmu^tm1.1Tomik involves: C57BL/6 * DBA	abnormal cardiovascular system morphology	J:235644
Trmu^tm1.1Tomik/Trmu^tm1.1Tomik involves: C57BL/6 * DBA	embryonic lethality between implantation and somite formation, complete penetrance	J:235644

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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