Tmem106b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tmem106b
transmembrane protein 106B
MGI:1919150

21 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tmem106b^em1(IMPC)Bay/Tmem106b^em1(IMPC)Bay C57BL/6N-Tmem106b^em1(IMPC)Bay/BayMmucd	abnormal retina inner nuclear layer morphology	J:211773
Tmem106b^em1Damme/Tmem106b^em1Damme C57BL/6-Tmem106b^em1Damme	abnormal axon initial segment morphology	J:288278
	abnormal axon morphology	J:288278
	abnormal lysosome morphology	J:288278
	abnormal motor capabilities/coordination/movement	J:288278
	abnormal motor neuron morphology	J:288278
	abnormal neuromuscular synapse morphology	J:288278
	abnormal orbicularis oculi muscle morphology	J:288278
	abnormal vibrissa morphology	J:288278
	normal embryo phenotype	J:288278
	normal growth/size/body region phenotype	J:288278
	impaired autophagy	J:288278
	impaired coordination	J:288278
	normal nervous system phenotype	J:288278
	spongiform encephalopathy	J:288278
Tmem106b^{tm2b(KOMP)Wtsi}/Tmem106b^{tm2b(KOMP)Wtsi} C57BL/6N-Tmem106b^{tm2b(KOMP)Wtsi}/Ucd	abnormal epididymis morphology	J:211773
	decreased body length	J:211773
	decreased brain weight	J:211773
	enlarged epididymis	J:211773
	increased bone mineral content	J:211773
	increased circulating alkaline phosphatase level	J:211773
Tmem106b^{tm2b(KOMP)Wtsi}/Tmem106b^{tm2b(KOMP)Wtsi} involves: C57BL/6N	spongiform encephalopathy	J:288278

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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