Gpr15 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gpr15
G protein-coupled receptor 15
MGI:1918473

21 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gpr15^em1(IMPC)J/Gpr15^em1(IMPC)J C57BL/6NJ-Gpr15^em1(IMPC)J/J	decreased bone mineral content	J:211773
	decreased lean body mass	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased mean corpuscular hemoglobin concentration	J:211773
	impaired glucose tolerance	J:211773
	increased total body fat amount	J:211773
Gpr15^tm1.1Litt/Gpr15^tm1.1Litt B6.129P2-Gpr15^tm1.1Litt	abnormal bone marrow cell physiology	J:199126
	abnormal regulatory T cell physiology	J:199126
	decreased CD4-positive, alpha-beta T cell number	J:199126
	decreased double-negative T cell number	J:199126
	decreased regulatory T cell number	J:199126
	normal immune system phenotype	J:199126
	increased CD8-positive, alpha-beta T cell number	J:199126
	increased susceptibility to bacterial infection	J:199126
	increased susceptibility to bacterial infection induced morbidity/mortality	J:199126
	increased susceptibility to induced colitis	J:199126
	increased susceptibility to weight loss	J:199126
	normal mortality/aging	J:156845
	normal reproductive system phenotype	J:156845
Gpr15^tm1.1Litt/Gpr15^tm1.1Litt involves: 129P2/OlaHsd * C57BL/6	decreased regulatory T cell number	J:199126
	increased interferon-gamma secretion	J:199126
	increased interleukin-17 secretion	J:199126

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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