Mex3b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mex3b
mex3 RNA binding family member B
MGI:1918252

26 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mex3b^tm1.1Mbld/Mex3b^tm1.1Mbld Plekha5^{Tg(AMH-cre)1Flor}/Plekha5⁺ involves: C57BL/6 * SJL	abnormal seminiferous tubule morphology	J:213588
	abnormal Sertoli cell barrier function	J:213588
	normal growth/size/body region phenotype	J:213588
	increased anti-sperm antibody level	J:213588
	increased Sertoli cell number	J:213588
	normal mortality/aging	J:213588
	reduced male fertility	J:213588
Mex3b^tm1.2Mbld/Mex3b^tm1.2Mbld involves: C57BL/6 * CBA	abnormal granulosa cell morphology	J:213588
	abnormal seminiferous tubule epithelium morphology	J:213588
	abnormal seminiferous tubule morphology	J:213588
	abnormal Sertoli cell barrier function	J:213588
	abnormal Sertoli cell barrier morphology	J:213588
	decreased body size	J:213588
	decreased body weight	J:213588
	decreased Sertoli cell phagocytosis	J:213588
	impaired macrophage phagocytosis	J:213588
	increased Sertoli cell number	J:213588
	neonatal lethality, incomplete penetrance	J:213588
	oligozoospermia	J:213588
	reduced fertility	J:213588
Mex3b^{tm1b(KOMP)Wtsi}/Mex3b^{tm1b(KOMP)Wtsi} C57BL/6N-Mex3b^{tm1b(KOMP)Wtsi}/Ccpcz	abnormal kidney morphology	J:211773
	abnormal ovary morphology	J:211773
	abnormal tooth morphology	J:211773
	abnormal vertebrae morphology	J:211773
	abnormal vertebral arch morphology	J:211773
	decreased body weight	J:211773
	hyperactivity	J:211773
	increased freezing behavior	J:211773
	preweaning lethality, incomplete penetrance	J:211773
	vertebral transformation	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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