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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Prickle1
prickle planar cell polarity protein 1
MGI:1916034
88 phenotypes from 8 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Prickle1b2b019Clo/Prickle1b2b019Clo
C57BL/6J-Prickle1b2b019Clo
cleft palate J:175213
double outlet right ventricle, ventricular defect committed to aorta J:175213
microcephaly J:175213
micrognathia J:175213
perimembraneous ventricular septal defect J:175213
Prickle1em1Yzou/Prickle1+
C57BL/6-Prickle1em1Yzou
abnormal excitatory synapse morphology J:321396
abnormal social investigation J:321396
abnormal spatial reference memory J:321396
increased susceptibility to pharmacologically induced seizures J:321396
Prickle1em1Yzou/Prickle1em1Yzou
C57BL/6-Prickle1em1Yzou
abnormal excitatory synapse morphology J:321396
abnormal object recognition memory J:321396
abnormal social investigation J:321396
Prickle1m1Ingm/Prickle1+
involves: C57BL/6
abnormal seizure response to electrical stimulation J:169136
Prickle1m1Ingm/Prickle1m1Ingm
involves: C57BL/6
normal mortality/aging J:169136
Prickle1m2Ingm/Prickle1+
C57BL/6-Prickle1m2Ingm
abnormal seizure response to electrical stimulation J:169136
Prickle1m2Ingm/Prickle1m2Ingm
C57BL/6-Prickle1m2Ingm
abnormal palatal mesenchymal cell proliferation J:223183
abnormal palatal rugae morphology J:223183
abnormal palatal shelf morphology J:223183
abnormal secondary palate development J:223183
cleft secondary palate J:223183
decreased maxillary shelf size J:223183
decreased palatal shelf size J:223183
failure of palatal shelf elevation J:223183
palatal shelves fail to meet at midline J:223183
prenatal lethality, complete penetrance J:169136
short snout J:223183
Prickle1tm1.2Asw/Prickle1tm1.2Asw
Not Specified
abnormal chondrocyte morphology J:213772
abnormal cochlear hair cell stereociliary bundle morphology J:213772
abnormal developmental patterning J:213772
abnormal digit morphology J:213772
abnormal fetal cardiomyocyte morphology J:213772
abnormal hair follicle morphology J:213772
abnormal hair follicle orientation J:213772
abnormal hippocampus morphology J:213772
abnormal innervation J:213772
abnormal kidney collecting duct morphology J:213772
abnormal kidney morphology J:213772
abnormal myocardial fiber morphology J:213772
abnormal nervous system tract morphology J:213772
abnormal nose morphology J:213772
abnormal phalanx morphology J:213772
abnormal proximal convoluted tubule morphology J:213772
abnormal renal tubule morphology J:213772
abnormal striatum morphology J:213772
abnormal ureteric bud morphology J:213772
atrial septal defect J:213772
bifid tongue J:213772
cleft palate J:213772
decreased body size J:213772
decreased length of long bones J:213772
delayed endochondral bone ossification J:213772
delayed neural tube closure J:213772
dilated renal tubule J:213772
embryonic lethality during organogenesis, incomplete penetrance J:213772
enlarged lateral ventricles J:213772
eyelids open at birth J:213772
increased diameter of long bones J:213772
increased heart right atrium size J:213772
kidney cyst J:213772
misaligned sternebrae J:213772
postnatal lethality, complete penetrance J:213772
short cochlear hair cell stereocilia J:213772
short forelimb J:213772
short limbs J:213772
short mandible J:213772
short nasal bone J:213772
short premaxilla J:213772
short snout J:213772
short tail J:213772
short tongue J:213772
transposition of great arteries J:213772
wavy tail J:213772
Prickle1tm1.2Asw/Prickle1tm1.3Asw
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * CBA
abnormal hair follicle development J:213772
abnormal hair follicle orientation J:213772
Prickle1tm1.3Asw/Prickle1tm1.3Asw
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * CBA
postnatal lethality, complete penetrance J:213772
Prickle1tm1Asw/Prickle1tm1.2Asw
Not Specified
abnormal eyelid cilium morphology J:213772
abnormal eyelid morphology J:213772
abnormal vertebrae development J:213772
brachydactyly J:213772
decreased body length J:213772
decreased length of long bones J:213772
flattened snout J:213772
fused lower incisors J:213772
kinked tail J:213772
ocular hypertelorism J:213772
prominent forehead J:213772
short snout J:213772
Prickle1tm1Asw/Prickle1tm1Asw
Not Specified
abnormal eyelid cilium morphology J:213772
abnormal eyelid morphology J:213772
abnormal vertebrae development J:213772
brachydactyly J:213772
decreased body length J:213772
decreased length of long bones J:213772
flattened snout J:213772
fused lower incisors J:213772
ocular hypertelorism J:213772
prominent forehead J:213772
short snout J:213772
Prickle1tm1Nue/Prickle1+
B6.Cg-Prickle1tm1Nue
abnormal seizure response to electrical stimulation J:169136
Prickle1tm1Nue/Prickle1tm1Nue
involves: C57BL/6 * CBA
abnormal anterior visceral endoderm cell migration J:151993
abnormal embryonic epiblast morphology J:151993
abnormal extraembryonic endoderm formation J:151993
abnormal mitotic spindle morphology J:151993
absent mesoderm J:151993
decreased mitotic index J:151993
embryonic growth arrest J:151993
embryonic lethality between somite formation and embryo turning, complete penetrance J:151993
failure of primitive streak formation J:151993
increased embryonic tissue cell apoptosis J:151993

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory