Upf3b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
MGI:1915384

24 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Upf3b^em1(IMPC)Tcp/Y C57BL/6NCrl-Upf3b^em1(IMPC)Tcp/Tcp	abnormal sternum morphology	J:211773
	decreased leukocyte cell number	J:211773
	decreased lymphocyte cell number	J:211773
	hyperactivity	J:211773
	increased fasting circulating glucose level	J:211773
	small kidney	J:211773
	small thymus	J:211773
Upf3b^em1(IMPC)Tcp/Upf3b^em1(IMPC)Tcp C57BL/6NCrl-Upf3b^em1(IMPC)Tcp/Tcp	abnormal stomach morphology	J:211773
	decreased freezing behavior	J:211773
	decreased lymphocyte cell number	J:211773
	hyperactivity	J:211773
	increased fasting circulating glucose level	J:211773
	increased neutrophil cell number	J:211773
	increased vertical activity	J:211773
	small thymus	J:211773
Upf3b^{Gt(IST14619B5)Tigm}/Y involves: C57BL/6J * C57BL/6N	abnormal sleep duration	J:253157
	abnormal sleep pattern	J:253157
	decreased dendritic spine density	J:253157
	decreased frequency of paradoxical sleep	J:253157
	decreased prepulse inhibition	J:253157
	decreased slow-wave sleep duration	J:253157
	decreased startle reflex	J:253157
	normal hearing/vestibular/ear phenotype	J:253157
	impaired contextual conditioning behavior	J:253157
	impaired cued conditioning behavior	J:253157
	impaired neuron differentiation	J:253157
	increased neuronal precursor proliferation	J:253157
	limb grasping	J:253157
Upf3b^{Gt(IST14619B5)Tigm}/Upf3b⁺ involves: C57BL/6J * C57BL/6N	impaired contextual conditioning behavior	J:253157
	impaired cued conditioning behavior	J:253157
Upf3b^{Gt(IST14619B5)Tigm}/Upf3b^{Gt(IST14619B5)Tigm} involves: C57BL/6J * C57BL/6N	abnormal sleep duration	J:253157
	abnormal sleep pattern	J:253157
	decreased dendritic spine density	J:253157
	decreased frequency of paradoxical sleep	J:253157
	decreased prepulse inhibition	J:253157
	decreased slow-wave sleep duration	J:253157
	decreased startle reflex	J:253157
	normal hearing/vestibular/ear phenotype	J:253157
	impaired contextual conditioning behavior	J:253157
	impaired cued conditioning behavior	J:253157
	impaired neuron differentiation	J:253157
	increased neuronal precursor proliferation	J:253157
	limb grasping	J:253157

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23