Ppp6c Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ppp6c
protein phosphatase 6, catalytic subunit
MGI:1915107

15 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ppp6c^tm1.1Shma/Ppp6c^tm1.1Shma involves: C57BL/6 * CBA	abnormal embryo development	J:231809
Ppp6c^tm1.1Shma/Ppp6c^tm1.1Shma involves: C57BL/6 * CBA	embryonic lethality, complete penetrance	J:231809
Ppp6c^{tm1b(EUCOMM)Hmgu}/Ppp6c⁺ C57BL/6N-Ppp6c^{tm1b(EUCOMM)Hmgu}/Ics	abnormal auditory brainstem response	J:211773
	abnormal locomotor behavior	J:211773
	abnormal vocalization	J:211773
	decreased blood urea nitrogen level	J:211773
	increased fasting circulating glucose level	J:211773
	increased mean corpuscular volume	J:211773
	short tibia	J:211773
Ppp6c^{tm1b(EUCOMM)Hmgu}/Ppp6c^{tm1b(EUCOMM)Hmgu} C57BL/6N-Ppp6c^{tm1b(EUCOMM)Hmgu}/Ics	preweaning lethality, complete penetrance	J:211773
Ppp6c^tm1Shma/Ppp6c^tm1Shma Tg(KRT14-cre/ERT)20Efu/0 involves: C57BL/6 * CBA * CD-1	decreased subcutaneous adipose tissue amount	J:231809
	hyperkeratosis	J:231809
	increased incidence of tumors by chemical induction	J:231809
	increased susceptibility to chemically induced skin inflammation	J:231809
	thick epidermis	J:231809

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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