Peli1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Peli1
pellino 1
MGI:1914495

30 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Peli1^tm1.1Arte/Peli1^tm1.1Arte involves: C57BL/6N	abnormal cytokine secretion	J:191578
	abnormal peripheral lymph node morphology	J:191578
	abnormal salivary gland morphology	J:191578
	decreased interferon-alpha secretion	J:191578
	decreased interferon-beta secretion	J:191578
	decreased interleukin-6 secretion	J:191578
	decreased interleukin-10 secretion	J:191578
	decreased interleukin-12 secretion	J:191578
	decreased tumor necrosis factor secretion	J:191578
	enlarged lymph nodes	J:191578
	normal immune system phenotype	J:191578
	lethality, incomplete penetrance	J:191578
	lymphoid hyperplasia	J:191578
Peli1^{tm1b(EUCOMM)Wtsi}/Peli1^{tm1b(EUCOMM)Wtsi} C57BL/6N-Peli1^{tm1b(EUCOMM)Wtsi}/Ucd	abnormal spleen morphology	J:211773
	decreased body length	J:211773
	decreased brain weight	J:211773
	enlarged heart	J:211773
	enlarged spleen	J:211773
	improved glucose tolerance	J:211773
	increased lean body mass	J:211773
	increased neutrophil cell number	J:211773
	increased spleen weight	J:211773
Peli1^tm1Tigm/Peli1^tm1Tigm involves: 129/Sv * C57BL/6	decreased B cell proliferation	J:152781
	decreased circulating interferon-beta level	J:152781
	decreased circulating interleukin-6 level	J:152781
	decreased circulating interleukin-12b level	J:152781
	decreased circulating tumor necrosis factor level	J:152781
	decreased interleukin-12 secretion	J:152781
	decreased susceptibility to endotoxin shock	J:152781
	decreased susceptibility to xenobiotic induced morbidity/mortality	J:152781
	increased B cell apoptosis	J:152781

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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