Mkrn2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mkrn2
makorin, ring finger protein, 2
MGI:1914277

19 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mkrn2^{em1(IMPC)Wtsi}/Mkrn2^{em1(IMPC)Wtsi} C57BL/6N-Mkrn2^{em1(IMPC)Wtsi}/WtsiOulu	decreased mean corpuscular hemoglobin concentration	J:211773
	male infertility	J:211773
Mkrn2^tm1.1Bhj/Mkrn2^tm1.1Bhj involves: 129P2/OlaHsd * C57BL/6J	abnormal acrosome morphology	J:250191
	abnormal ectoplasmic specialization morphology	J:250191
	abnormal outer dense fiber morphology	J:250191
	abnormal sperm axoneme morphology	J:250191
	abnormal sperm flagellum morphology	J:250191
	abnormal sperm head morphology	J:250191
	abnormal spermatid morphology	J:250191
	abnormal spermiation	J:250191
	absent acrosome	J:250191
	asthenozoospermia	J:250191
	decreased body weight	J:250191
	decreased male germ cell number	J:250191
	decreased testis weight	J:250191
	male infertility	J:250191
	oligozoospermia	J:250191
Mkrn2^{tm1b(KOMP)Wtsi}/Mkrn2^{tm1b(KOMP)Wtsi} C57BL/6N-Mkrn2^{tm1b(KOMP)Wtsi}/Wtsi	abnormal auditory brainstem response	J:211773
	decreased dendritic epidermal T cell number	J:211773
	increased circulating aspartate transaminase level	J:211773
	male infertility	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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