Sdhd Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sdhd
succinate dehydrogenase complex, subunit D, integral membrane protein
MGI:1914175

21 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sdhd^tm1Jlob/Sdhd⁺ involves: 129X1/SvJ	abnormal carotid body physiology	J:95252
	abnormal respiratory electron transport chain	J:95252
	abnormal type I cell of carotid body morphology	J:95252
	abnormal type I cell of carotid body physiology	J:95252
	normal neoplasm	J:95252
Sdhd^tm1Jlob/Sdhd^tm1Jlob involves: 129X1/SvJ	embryonic growth arrest	J:95252
Sdhd^tm1Jlob/Sdhd^tm1Jlob involves: 129X1/SvJ	embryonic lethality between implantation and somite formation, complete penetrance	J:95252
Sdhd^tm1Jlob/Sdhd^tm2Jlob Tg(CAG-cre/Esr1)5Amc/0 involves: 129S1/Sv 129X1/SvJ * C57BL/6 * CBA	abnormal carotid body morphology	J:186713
	normal neoplasm	J:186713
	normal nervous system phenotype	J:186713
	premature death	J:186713
Sdhd^tm1Jlob/Sdhd^tm2Jlob Th^tm1(cre)Te/Th⁺ involves: 129S1/Sv * 129X1/SvJ	abnormal adrenal chromaffin cell morphology	J:186713
	abnormal dopaminergic neuron morphology	J:186713
	bradykinesia	J:186713
	decreased birth body size	J:186713
	decreased dopamine level	J:186713
	decreased locomotor activity	J:186713
	decreased neuron number	J:186713
	loss of dopaminergic neurons	J:186713
	normal neoplasm	J:186713
	oxidative stress	J:186713
	premature death	J:186713
Sdhd^tm1Jpb/Sdhd⁺ either: 129P2/OlaHsd-Sdhd^tm1Jpb or (involves: 129P2/OlaHsd * C57BL/6J)	no abnormal phenotype detected	J:155380
Sdhd^tm1Jpb/Sdhd^tm1Jpb 129P2/OlaHsd-Sdhd^tm1Jpb	embryonic lethality, complete penetrance	J:155380

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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