Wwp2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Wwp2
WW domain containing E3 ubiquitin protein ligase 2
MGI:1914144

13 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Wwp2^em1Asah/Wwp2^em1Asah involves: C57BL/6J * DBA	normal craniofacial phenotype	J:278573
Wwp2^{Gt(HMA140)Byg}/Wwp2^em1Asah involves: 129P2/OlaHsd * C57BL/6J * DBA	normal craniofacial phenotype	J:278573
Wwp2^{Gt(HMA140)Byg}/Wwp2^{Gt(HMA140)Byg} B6.129P2-Wwp2^{Gt(HMA140)Byg}	abnormal jaw morphology	J:228709
	abnormal snout morphology	J:228709
	decreased body size	J:228709
	domed cranium	J:228709
	long lower incisors	J:228709
	short nasal bone	J:228709
	short snout	J:228709
Wwp2^tm1.1Yyiw/Wwp2^tm1.1Yyiw involves: 129S/SvEv * C57BL/6 * FVB/N	normal immune system phenotype	J:228707
	increased circulating interferon-beta level	J:228707
	increased circulating interleukin-6 level	J:228707
	increased circulating tumor necrosis factor level	J:228707
	increased susceptibility to xenobiotic induced morbidity/mortality	J:228707

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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