About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Foxo4
forkhead box O4
MGI:1891915
20 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Foxo1tm1Rdp/Foxo1tm1Rdp
Foxo3tm1Rdp/Foxo3tm1Rdp
Foxo4tm1Rdp/Foxo4tm1Rdp
Tg(Ins2-cre)23Herr/0
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * CBA/J 		abnormal glucose homeostasis J:215526
abnormal mitochondrial physiology J:215526
abnormal pancreatic beta cell differentiation J:215526
abnormal pancreatic beta cell physiology J:215526
decreased circulating insulin level J:215526
decreased insulin secretion J:215526
hyperglycemia J:215526
impaired glucose tolerance J:215526
Foxo1tm1Rdp/Foxo1tm1Rdp
Foxo3tm1Rdp/Foxo3tm1Rdp
Foxo4tm1Rdp/Foxo4tm1Rdp
Tg(Mx1-cre)1Cgn/0
involves: 129S6/SvEvTac * C57BL/6 * CBA * FVB/N 		increased hamartoma incidence J:118179
increased hemangioma incidence J:118179
increased hemangiosarcoma incidence J:118179
increased T cell derived lymphoma incidence J:118179
premature death J:118179
Foxo1tm1Rdp/Foxo1tm1Rdp
Foxo4tm1Rdp/Foxo4tm1Rdp
Tg(Mx1-cre)1Cgn/0
involves: 129S6/SvEvTac * C57BL/6 * CBA * FVB/N 		increased hamartoma incidence J:118179
increased hemangioma incidence J:118179
increased hemangiosarcoma incidence J:118179
increased hepatic hemangioma incidence J:118179
premature death J:118179
Foxo3tm1.1Rdp/Foxo3+
Foxo4tm1.1Rdp/Foxo4tm1.1Rdp
involves: 129S1/Sv * 129S6/SvEvTac * FVB/N 		increased Harderian gland tumor incidence J:118179
increased ovary tumor incidence J:118179
increased pituitary adenoma incidence J:118179
increased tumor incidence J:118179
Foxo3tm1.1Rdp/Foxo3tm1.1Rdp
Foxo4tm1.1Rdp/Foxo4tm1.1Rdp
involves: 129S1/Sv * 129S6/SvEvTac * FVB/N 		increased Harderian gland tumor incidence J:118179
increased lung adenoma incidence J:118179
increased ovarian teratoma incidence J:118179
increased ovary tumor incidence J:118179
increased pituitary adenoma incidence J:118179
increased tumor incidence J:118179
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory