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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Foxo4
forkhead box O4
MGI:1891915
20 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Foxo1tm1Rdp/Foxo1tm1Rdp
Foxo3tm1Rdp/Foxo3tm1Rdp
Foxo4tm1Rdp/Foxo4tm1Rdp
Tg(Ins2-cre)23Herr/0
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * CBA/J
abnormal glucose homeostasis J:215526
abnormal mitochondrial physiology J:215526
abnormal pancreatic beta cell differentiation J:215526
abnormal pancreatic beta cell physiology J:215526
decreased circulating insulin level J:215526
decreased insulin secretion J:215526
hyperglycemia J:215526
impaired glucose tolerance J:215526
Foxo1tm1Rdp/Foxo1tm1Rdp
Foxo3tm1Rdp/Foxo3tm1Rdp
Foxo4tm1Rdp/Foxo4tm1Rdp
Tg(Mx1-cre)1Cgn/0
involves: 129S6/SvEvTac * C57BL/6 * CBA * FVB/N
increased hamartoma incidence J:118179
increased hemangioma incidence J:118179
increased hemangiosarcoma incidence J:118179
increased T cell derived lymphoma incidence J:118179
premature death J:118179
Foxo1tm1Rdp/Foxo1tm1Rdp
Foxo4tm1Rdp/Foxo4tm1Rdp
Tg(Mx1-cre)1Cgn/0
involves: 129S6/SvEvTac * C57BL/6 * CBA * FVB/N
increased hamartoma incidence J:118179
increased hemangioma incidence J:118179
increased hemangiosarcoma incidence J:118179
increased hepatic hemangioma incidence J:118179
premature death J:118179
Foxo3tm1.1Rdp/Foxo3+
Foxo4tm1.1Rdp/Foxo4tm1.1Rdp
involves: 129S1/Sv * 129S6/SvEvTac * FVB/N
increased Harderian gland tumor incidence J:118179
increased ovary tumor incidence J:118179
increased pituitary adenoma incidence J:118179
increased tumor incidence J:118179
Foxo3tm1.1Rdp/Foxo3tm1.1Rdp
Foxo4tm1.1Rdp/Foxo4tm1.1Rdp
involves: 129S1/Sv * 129S6/SvEvTac * FVB/N
increased Harderian gland tumor incidence J:118179
increased lung adenoma incidence J:118179
increased ovarian teratoma incidence J:118179
increased ovary tumor incidence J:118179
increased pituitary adenoma incidence J:118179
increased tumor incidence J:118179

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/11/2018
MGI 6.12
The Jackson Laboratory