Lgr4 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lgr4
leucine-rich repeat-containing G protein-coupled receptor 4
MGI:1891468

14 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Lgr4^{tm1.1(cre/ERT2)Npa}/Lgr4^{tm1.1(cre/ERT2)Npa} Lgr5^{tm1.1(cre/ERT2)Npa}/Lgr5^{tm1.1(cre/ERT2)Npa} involves: C57BL/6	abnormal epidermal stem cell proliferation	J:212415
	abnormal hair follicle development	J:212415
	abnormal intestine development	J:212415
	abnormal intestine physiology	J:212415
	abnormal skin development	J:212415
	decreased hair follicle number	J:212415
	decreased kidney cell proliferation	J:212415
	perinatal lethality, complete penetrance	J:212415
	prenatal lethality, incomplete penetrance	J:212415
	normal renal/urinary system phenotype	J:212415
	thin epidermis	J:212415
Lgr4^tm1.1Knis/Lgr4^tm1.1Knis Lgr5^tm2.1Cle/Lgr5^tm2.1Cle Tg(Cyp1a1-cre)1Dwi/0 involves: 129P2/OlaHsd * C57BL/6 * CBA	abnormal small intestinal crypt cell proliferation	J:174842
	decreased small intestinal villus size	J:174842
	premature death	J:174842
Lgr4^tm1.1Knis/Lgr4^tm1.1Knis Lgr5^tm2.1Cle/Lgr5^tm2.1Cle Tg(Vil1-cre/ERT2)23Syr/0 involves: 129P2/OlaHsd * C57BL/6 * DBA/2	abnormal intestine physiology	J:174842

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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