Lrat Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lrat
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
MGI:1891259

18 phenotypes from 5 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lrat^{tm1.1(KOMP)Vlcg}/Lrat^{tm1.1(KOMP)Vlcg} C57BL/6N-Lrat^{tm1.1(KOMP)Vlcg}/Ucd	preweaning lethality, incomplete penetrance	J:211773
Lrat^tm1.1Bok/Lrat^tm1.1Bok involves: 129S2/SvPas	abnormal eye electrophysiology	J:132516
	abnormal vitamin A level	J:132516
	short photoreceptor outer segment	J:132516
Lrat^tm1Bok/Lrat^tm1Bok Tg(Tyrp1-cre)1Ipc/? involves: 129S2/SvPas	abnormal eye electrophysiology	J:132516
	abnormal vitamin A level	J:132516
	short photoreceptor outer segment	J:132516
Lrat^tm1Kpal/Lrat⁺ involves: 129S6/SvEvTac	abnormal vitamin A metabolism	J:88871
Lrat^tm1Kpal/Lrat⁺ involves: 129S6/SvEvTac	normal vision/eye phenotype	J:88871
Lrat^tm1Kpal/Lrat^tm1Kpal involves: 129S6/SvEvTac	abnormal retina cone cell outer segment morphology	J:136882
	abnormal retina photoreceptor morphology	J:136882
	retina cone cell degeneration	J:136882
	retina photoreceptor degeneration	J:136882
	retina rod cell degeneration	J:136882
	short photoreceptor outer segment	J:136882
	thin retina outer nuclear layer	J:170648
Lrat^tm1Log/Lrat^tm1Log involves: 129S1/Sv * C57BL/6J	abnormal retinol level	J:104101
	abnormal testis morphology	J:104101
	abnormal vitamin A level	J:104101
	dilated seminiferous tubule	J:104101
	oligozoospermia	J:104101
	testicular atrophy	J:104101
	testis hypoplasia	J:104101

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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