Kcne2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kcne2
potassium voltage-gated channel, Isk-related subfamily, gene 2
MGI:1891123

31 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kcne2^{tm1a(EUCOMM)Wtsi}/Kcne2^{tm1a(EUCOMM)Wtsi} C57BL/6N-Kcne2^{tm1a(EUCOMM)Wtsi}	abnormal gastric chief cell morphology	J:230226
	abnormal gastric parietal cell morphology	J:230226
	anemia	J:230226
	decreased circulating ferritin level	J:230226
	decreased circulating iron level	J:230226
	decreased erythrocyte cell number	J:230226
	decreased hematocrit	J:230226
	decreased hemoglobin content	J:230226
	decreased mean corpuscular hemoglobin	J:230226
	decreased mean corpuscular volume	J:230226
	decreased spleen iron level	J:230226
	gastric gland hyperplasia	J:230226
	normal hematopoietic system phenotype	J:230226
	normal homeostasis/metabolism phenotype	J:230226
	hypochromic microcytic anemia	J:230226
	increased adenoma incidence	J:230226
	increased circulating erythropoietin level	J:230226
	increased circulating magnesium level	J:230226
	increased red blood cell distribution width	J:230226
	increased stomach pH	J:230226
	stomach inflammation	J:230226
	thrombocytosis	J:230226
Kcne2^{tm1a(EUCOMM)Wtsi}/Kcne2^{tm1a(EUCOMM)Wtsi} C57BL/6N-Kcne2^{tm1a(EUCOMM)Wtsi}/Wtsi	decreased body weight	J:175295
	decreased circulating iron level	J:175295
	decreased erythrocyte cell number	J:175295
	increased circulating magnesium level	J:175295
Kcne2^tm1Gwab/Kcne2⁺ involves: 129S4/SvJae * C57BL/6	decreased digestive secretion	J:116518
	normal digestive/alimentary phenotype	J:116518
	normal homeostasis/metabolism phenotype	J:116518
	hypochlorhydria	J:116518
	increased stomach pH	J:116518
Kcne2^tm1Gwab/Kcne2^tm1Gwab involves: 129S4/SvJae	achlorhydria	J:170745
	enlarged stomach	J:170745
	increased stomach pH	J:170745
Kcne2^tm1Gwab/Kcne2^tm1Gwab involves: 129S4/SvJae * C57BL/6	abnormal gastric parietal cell morphology	J:116518
	abnormal stomach glandular epithelium morphology	J:116518
	abnormal stomach glandular region morphology	J:116518
	achlorhydria	J:116518
	decreased digestive secretion	J:116518
	enlarged stomach	J:116518
	gastric gland hyperplasia	J:116518
	increased circulating gastrin level	J:116518
	increased stomach pH	J:116518

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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