Brwd1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Brwd1
bromodomain and WD repeat domain containing 1
MGI:1890651

24 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Brwd1^em1(IMPC)Tcp/Brwd1^em1(IMPC)Tcp C57BL/6NCrl-Brwd1^em1(IMPC)Tcp/Tcp	abnormal seminal vesicle morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	female infertility	J:211773
	increased circulating cholesterol level	J:211773
	increased circulating HDL cholesterol level	J:211773
	male infertility	J:211773
	small testis	J:211773
Brwd1^{Gt(AW0417)Wtsi}/Brwd1^{Gt(AW0417)Wtsi} involves: 129P2/OlaHsd	abnormal female meiosis	J:136078
	abnormal male germ cell morphology	J:136078
	decreased male germ cell number	J:136078
Brwd1^{Gt(AW0417)Wtsi}/Brwd1^repro5 involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J	asthenozoospermia	J:136078
	decreased male germ cell number	J:136078
	globozoospermia	J:136078
Brwd1^repro5/Brwd1^repro5 involves: C3HeB/FeJ * C57BL/6J	abnormal female meiosis	J:136078
	abnormal male germ cell morphology	J:136078
	abnormal oocyte morphology	J:92463
	abnormal reproductive system morphology	J:136078
	abnormal reproductive system physiology	J:136078
	abnormal sperm flagellum morphology	J:136078
	abnormal sperm head morphology	J:136078
	abnormal sperm midpiece morphology	J:136078
	abnormal spermiogenesis	J:92463
	asthenozoospermia	J:92463, J:136078
	female infertility	J:92463, J:136078
	globozoospermia	J:92463, J:136078
	impaired fertilization	J:136078
	male infertility	J:92463, J:136078
	necrospermia	J:136078
	oligozoospermia	J:92463
	teratozoospermia	J:136078

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23