Scube1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Scube1
signal peptide, CUB domain, EGF-like 1
MGI:1890616

31 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Scube1^{em1(IMPC)Rbrc}/Scube1^{em1(IMPC)Rbrc} C57BL/6NJcl-Scube1^{em1(IMPC)Rbrc}/Rbrc	abnormal brain morphology	J:211773
	female infertility	J:211773
	hydrocephaly	J:211773
	male infertility	J:211773
Scube1^tm1Rbya/Scube1^tm1Rbya involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal brain morphology	J:136534
	abnormal cranial ganglia morphology	J:136534
	abnormal diencephalon morphology	J:136534
	abnormal forebrain morphology	J:136534
	abnormal medulla oblongata morphology	J:136534
	abnormal neural tube closure	J:136534
	abnormal trigeminal ganglion morphology	J:136534
	abnormal vestibular ganglion morphology	J:136534
	absent interparietal bone	J:136534
	absent neurocranium	J:136534
	absent supraoccipital bone	J:136534
	acrania	J:136534
	everted embryonic neuroepithelium	J:136534
	exencephaly	J:136534
	increased embryonic neuroepithelial cell proliferation	J:136534
	increased embryonic neuroepithelium thickness	J:136534
	neonatal lethality, complete penetrance	J:136534
	small alisphenoid bone	J:136534
	small frontal bone	J:136534
	small parietal bone	J:136534
	small temporal bone squamous part	J:136534
Scube1^tm2.1Rbya/Scube1^tm2.1Rbya Not Specified	normal cardiovascular system phenotype	J:223899
	decreased platelet aggregation	J:223899
	decreased susceptibility to induced morbidity/mortality	J:223899
	decreased susceptibility to induced thrombosis	J:223899
	normal hematopoietic system phenotype	J:223899
	normal homeostasis/metabolism phenotype	J:223899
	increased bleeding time	J:223899

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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