Nub1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nub1
negative regulator of ubiquitin-like proteins 1
MGI:1889001

27 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Nub1^{tm1b(EUCOMM)Hmgu}/Nub1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Nub1^{tm1b(EUCOMM)Hmgu}/Ccpcz	abnormal coat appearance	J:211773
	abnormal heart morphology	J:211773
	abnormal lens morphology	J:211773
	abnormal optic disk morphology	J:211773
	abnormal retina blood vessel morphology	J:211773
	abnormal retina morphology	J:211773
	abnormal retina vasculature morphology	J:211773
	abnormal spleen morphology	J:211773
	decreased CD4-negative NK T cell number	J:211773
	decreased CD4-positive, alpha-beta T cell number	J:211773
	decreased CD5-positive Ly6C-positive T cell number	J:211773
	decreased CD8-positive, alpha-beta T cell number	J:211773
	decreased CD11b-high dendritic cell number	J:211773
	decreased circulating iron level	J:211773
	decreased Ly6C-positive NK T cell number	J:211773
	decreased memory-marker CD4-negative NK T cell number	J:211773
	decreased NK cell number	J:211773
	decreased NK T cell number	J:211773
	enlarged spleen	J:211773
	immune system phenotype	J:211773
	increased circulating potassium level	J:211773
	increased effector memory CD8-positive, alpha-beta T cell number	J:211773
	increased effector memory T-helper cell number	J:211773
	increased freezing behavior	J:211773
	increased heart atrium size	J:211773
	increased Ly6C-positive NK T cell number	J:211773
	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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