Cxcl13 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cxcl13
C-X-C motif chemokine ligand 13
MGI:1888499

21 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cxcl13^em2(IMPC)H/Cxcl13^em2(IMPC)H C57BL/6NTac-Cxcl13^em2(IMPC)H/H	increased basophil cell number	J:211773
	increased leukocyte cell number	J:211773
	increased lymphocyte cell number	J:211773
Cxcl13^m1Btlr/Cxcl13^m1Btlr C57BL/6J-Cxcl13^m1Btlr	increased B-1 B cell number	J:221480
Cxcl13^tm1Cys/Cxcl13^tm1Cys B6.129X1-Cxcl13^tm1Cys	abnormal B cell physiology	J:118931
Cxcl13^tm1Cys/Cxcl13^tm1Cys involves: 129X1/SvJ * C57BL/6	abnormal B cell physiology	J:78282
	abnormal lymph node germinal center morphology	J:78282
	abnormal Peyer's patch morphology	J:78282
	abnormal spleen B cell follicle morphology	J:78282
	abnormal spleen marginal zone morphology	J:78282
	absent axillary lymph nodes	J:78282
	absent brachial lymph nodes	J:78282
	absent follicular dendritic cells	J:78282
	absent inguinal lymph nodes	J:78282
	decreased lymph node number	J:78282
	decreased Peyer's patch number	J:78282
	decreased spleen germinal center size	J:78282
	small Peyer's patches	J:78282
Cxcl13^tm1Mmi/Cxcl13^tm1Mmi involves: C57BL/6	abnormal B cell physiology	J:84804
	abnormal leukocyte adhesion	J:84804
	abnormal leukocyte migration	J:84804
Tg(Ins2-Cxcl13)1Cys/0 involves: C57BL/6 * DBA/2	abnormal lymph organ development	J:110548
Tg(Ins2-Cxcl13)1Cys/0 involves: C57BL/6 * DBA/2	abnormal pancreatic islet morphology	J:77238, J:110548

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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