Gtf2ird1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gtf2ird1
general transcription factor II I repeat domain-containing 1
MGI:1861942

31 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Gtf2ird1^{Tg(Alb1-Myc)166.8Sst}/Gtf2ird1⁺ involves: C57BL/6 * CBA	abnormal hepatocyte morphology	J:34434
	increased hepatocellular carcinoma incidence	J:34434, J:101128
	increased liver adenoma incidence	J:34434
	increased liver tumor incidence	J:101128
	increased liver weight	J:34434
Gtf2ird1^{Tg(Alb1-Myc)166.8Sst}/Gtf2ird1⁺ involves: C57BL/6J * CBA/J	abnormal circadian behavior	J:190478
	abnormal eating behavior	J:190478
	decreased body weight	J:190478
	impaired coordination	J:190478
	postnatal growth retardation	J:190478
	slow postnatal weight gain	J:190478
Gtf2ird1^{Tg(Alb1-Myc)166.8Sst}/Gtf2ird1⁺ Tg(MtTGFA)42Lmb/0 involves: C57BL/6 * CBA * CD-1	abnormal hepatocyte morphology	J:34434
	increased hepatocellular carcinoma incidence	J:34434
	increased hepatocyte apoptosis	J:34434
	increased hepatocyte karyomegaly	J:34434
	increased liver adenoma incidence	J:34434
	increased liver weight	J:34434
	multifocal hepatic necrosis	J:34434
Gtf2ird1^{Tg(Alb1-Myc)166.8Sst}/Gtf2ird1⁺ Tg(Alb-E2F1)8Sst/0 involves: C57BL/6 * CBA	increased hepatocellular carcinoma incidence	J:101128
	increased liver tumor incidence	J:101128
Gtf2ird1^{Tg(Alb1-Myc)166.8Sst}/Gtf2ird1^{Tg(Alb1-Myc)166.8Sst} involves: C57BL/6 * CBA	abnormal mastication	J:102709
	asymmetric snout	J:102709
	decreased body weight	J:102709
	limb grasping	J:102709
	malocclusion	J:102709
	periorbital fullness	J:102709
	short snout	J:102709
Gtf2ird1^{Tg(Alb1-Myc)166.8Sst}/Gtf2ird1^{Tg(Alb1-Myc)166.8Sst} involves: C57BL/6J * CBA/J	abnormal circadian behavior	J:190478
	abnormal eating behavior	J:190478
	abnormal fear/anxiety-related behavior	J:190478
	abnormal gait	J:190478
	abnormal jaw morphology	J:190478
	abnormal nest building behavior	J:190478
	abnormal response to new environment	J:190478
	decreased body weight	J:190478
	decreased grip strength	J:190478
	decreased vertical activity	J:190478
	impaired coordination	J:190478
	increased anxiety-related response	J:190478
	increased circulating corticosterone level	J:190478
	increased grooming behavior	J:190478
	increased response to stress-induced hyperthermia	J:190478
	limb grasping	J:190478
	periorbital fullness	J:190478
	postnatal growth retardation	J:190478
	short snout	J:190478
	slow postnatal weight gain	J:190478
Gtf2ird1^{Tg(Alb1-Myc)166.8Sst}/0 Tg(MtTGFA)42Lmb/0 involves: C57BL/6 * CBA * CD-1	increased hepatocellular carcinoma incidence	J:4527

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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