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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ubr2
ubiquitin protein ligase E3 component n-recognin 2
MGI:1861099
23 phenotypes from 2 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ubr2tm1e.1(KOMP)Mbp/Ubr2+
C57BL/6N-Ubr2tm1e.1(KOMP)Mbp/Tcp 		abnormal heart morphology J:211773
abnormal liver morphology J:211773
enlarged heart J:211773
hemorrhage J:211773
microcephaly J:211773
microphthalmia J:211773
polydactyly J:211773
spina bifida J:211773
syndactyly J:211773
Ubr2tm1e.1(KOMP)Mbp/Ubr2tm1e.1(KOMP)Mbp
C57BL/6N-Ubr2tm1e.1(KOMP)Mbp/Tcp 		hemorrhage J:211773
microcephaly J:211773
microphthalmia J:211773
polydactyly J:211773
preweaning lethality, complete penetrance J:211773
preweaning lethality, incomplete penetrance J:211773
spina bifida J:211773
syndactyly J:211773
Ubr2tm1Ytkw/Ubr2tm1Ytkw
involves: 129S1/Sv 		prenatal lethality, incomplete penetrance J:86438
testis degeneration J:86438
Ubr2tm1Ytkw/Ubr2tm1Ytkw
involves: 129S1/Sv * C57BL/6 		abnormal embryonic tissue morphology J:86438
abnormal embryonic tissue physiology J:86438
abnormal fertility/fecundity J:86438
abnormal gametogenesis J:86438
arrest of male meiosis J:86438
increased embryonic tissue cell apoptosis J:86438
male infertility J:86438
oligozoospermia J:86438
postnatal growth retardation J:86438
prenatal lethality, incomplete penetrance J:86438
reduced female fertility J:86438
testis degeneration J:86438
Ubr2tm1Ytkw/Ubr2tm1Ytkw
involves: 129S1/Sv * CD-1 		prenatal lethality, incomplete penetrance J:86438
testis degeneration J:86438
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory