Septin9 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Septin9
septin 9
MGI:1858222

18 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Septin9^tm1Emfu/Septin9^tm1Emfu Not Specified	embryonic lethality during organogenesis, complete penetrance	J:205180
Septin9^tm1Emfu/Septin9^tm1Emfu Not Specified	increased apoptosis	J:205180
Septin9^tm1Emfu/Septin9^tm2.2Emfu Not Specified	embryonic lethality during organogenesis, complete penetrance	J:205180
Septin9^tm1Emfu/Septin9^tm2.2Emfu Not Specified	increased apoptosis	J:205180
Septin9^tm2.1Emfu/Septin9^tm2.1Emfu Not Specified	no abnormal phenotype detected	J:205180
Septin9^tm2.1Emfu/Septin9^tm2.1Emfu Cnp^tm1(cre)Kan/Cnp⁺ involves: 129S1/Sv * 129X1/SvJ	normal nervous system phenotype	J:339068
Septin9^tm2.1Emfu/Septin9^tm2.1Emfu Tg(Dhh-cre)1Mejr/0 involves: 129S1/Sv * FVB/N	normal behavior/neurological phenotype	J:339068
	normal nervous system phenotype	J:339068
Septin9^tm2.1Emfu/Septin9^tm2.1Emfu Tg(Lck-cre)548Jxm/0 involves: C57BL/6 * CBA	abnormal T cell differentiation	J:205027
	decreased CD4-positive, alpha-beta memory T cell number	J:205027
	decreased CD4-positive, alpha-beta T cell number	J:205027
	decreased CD8-positive, alpha-beta memory T cell number	J:205027
	decreased CD8-positive, alpha-beta T cell number	J:205027
	decreased DN4 thymocyte number	J:205027
	decreased regulatory T cell number	J:205027
	decreased single-positive T cell number	J:205027
	decreased T cell number	J:205027
	decreased T cell proliferation	J:205027
	increased CD8-positive, alpha-beta memory T cell number	J:205027
	increased DN3 thymocyte number	J:205027
	increased double-negative T cell number	J:205027
Septin9^tm2.1Emfu/Septin9^tm2.1Emfu Tg(Mx1-cre)1Cgn/0 involves: C57BL/6 * CBA	decreased CD8-positive, alpha-beta T cell number	J:205027
Septin9^tm2.2Emfu/Septin9^tm2.2Emfu Not Specified	embryonic lethality during organogenesis, complete penetrance	J:205180
Septin9^tm2.2Emfu/Septin9^tm2.2Emfu Not Specified	increased apoptosis	J:205180

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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