70 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Acvr1tm1Mak/Acvr1+ Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Olig2tm1.1(cre)Wdr/Olig2+ involves: 129 * C57BL/6	increased oligodendrocyte number	J:285841
Acvr1tm1Mak/Acvr1+ Olig2tm1.1(cre)Wdr/Olig2+ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal brain development	J:285841
	abnormal brainstem morphology	J:285841
	abnormal glial cell physiology	J:285841
	ataxia	J:285841
	muscle spasm	J:285841
	normal neoplasm	J:285841
	preweaning lethality, incomplete penetrance	J:285841
Acvr1tm1Mak/Acvr1+ Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+ Olig2tm1.1(cre)Wdr/Olig2+ involves: 129 * C57BL/6 * FVB/N	increased brain tumor incidence	J:285841
	increased glioma incidence	J:285841
Acvr1tm1Mak/Acvr1+ Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+ H3c2tm1Mak/H3c2+ Olig2tm1.1(cre)Wdr/Olig2+ involves: 129 * C57BL/6 * FVB/N	increased brain tumor incidence	J:285841
	increased glioma incidence	J:285841
Acvr1tm1Mak/Acvr1+ H3c2tm1Mak/H3c2+ Olig2tm1.1(cre)Wdr/Olig2+ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6	normal neoplasm	J:285841
	postnatal lethality, incomplete penetrance	J:285841
Cdh2tm1Glr/Cdh2tm1Glr Olig2tm1(cre)Tmj/Olig2+ involves: 129S6/SvEvTac	abnormal neuronal migration	J:178688
	abnormal spinal cord morphology	J:178688
	abnormal spinal cord motor column morphology	J:178688
	lethality throughout fetal growth and development, incomplete penetrance	J:178688
	neonatal lethality, complete penetrance	J:178688
Cspg4tm1Ychan/Cspg4tm1Ychan Olig2tm2(TVA,cre)Rth/Olig2+ involves: 129 * C57BL/6N	decreased body weight	J:184220
	decreased epididymal fat pad weight	J:184220
Ctnnb1tm2Kem/Ctnnb1tm2Kem Juptm1Ruiz/Juptm1.1Tmj Olig2tm1(cre)Tmj/Olig2+ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	abnormal dendrite morphology	J:178688
	lethality throughout fetal growth and development, complete penetrance	J:178688
Ctnnb1tm2Kem/Ctnnb1tm2Kem Juptm1Ruiz/Juptm1Ruiz Olig2tm1(cre)Tmj/Olig2+ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	abnormal neuronal migration	J:178688
	abnormal spinal cord lateral motor column morphology	J:178688
	abnormal spinal cord medial motor column morphology	J:178688
	abnormal spinal cord motor column morphology	J:178688
	abnormal ventral interneuron 1 morphology	J:178688
	abnormal ventral interneuron 2 morphology	J:178688
	decreased motor neuron number	J:178688
	embryonic lethality during organogenesis, complete penetrance	J:178688
	normal nervous system phenotype	J:178688
Ctnnb1tm2Kem/Ctnnb1tm2Kem Olig2tm1(cre)Tmj/Olig2+ involves: 129S1/Sv * 129X1/SvJ	abnormal spinal cord medial motor column morphology	J:178688
	decreased motor neuron number	J:178688
	neonatal lethality, complete penetrance	J:178688
Gt(ROSA)26Sorem2(Mios)Bcgen/Gt(ROSA)26Sor+ Miostm1Pfw/Miostm1Pfw Olig2tm2(TVA,cre)Rth/Olig2+ involves: 129 * C57BL/6	normal nervous system phenotype	J:320720
Gt(ROSA)26Sortm1(Hoxa2)Fmr/Gt(ROSA)26Sor+ Olig2tm2(TVA,cre)Rth/Olig2+ involves: 129P2/OlaHsd	abnormal brain development	J:193058
	decreased oligodendrocyte progenitor number	J:193058
Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+ Olig2tm1.1(cre)Wdr/Olig2+ involves: 129 * C57BL/6 * FVB/N	normal neoplasm	J:285841
Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+ H3c2tm1Mak/H3c2+ Olig2tm1.1(cre)Wdr/Olig2+ involves: 129 * C57BL/6 * FVB/N	normal neoplasm	J:285841
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm1(Smo/EYFP)Amc Olig2tm2(TVA,cre)Rth/Olig2+ involves: 129 * 129X1/SvJ	increased medulloblastoma incidence	J:139574
	premature death	J:139574
Mapttm1(Sema3e)Yuyo/Mapt+ Olig2tm1(cre)Tmj/Olig2+ Not Specified	abnormal excitatory postsynaptic potential	J:205528
	abnormal sensory neuron innervation pattern	J:205528
	abnormal synaptic bouton morphology	J:205528
	normal nervous system phenotype	J:205528
Miostm1Pfw/Miostm1Pfw Olig2tm2(TVA,cre)Rth/Olig2+ involves: 129 * C57BL/6	abnormal oligodendrocyte physiology	J:320720
	normal behavior/neurological phenotype	J:320720
	decreased oligodendrocyte number	J:320720
	dysmyelination	J:320720
Myrftm1Barr/Myrftm1Barr Olig2tm2(TVA,cre)Rth/Olig2+ involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6	abnormal myelination	J:150563
	abnormal optic nerve morphology	J:150563
	abnormal spinal cord morphology	J:150563
	ataxia	J:150563
	normal nervous system phenotype	J:150563
	postnatal lethality, complete penetrance	J:150563
	seizures	J:150563
	tremors	J:150563
Ntf3tm2.1Jae/Ntf3tm2Jae Olig2tm2(cre)Htak/Olig2+ Not Specified	abnormal dorsal root ganglion morphology	J:182750
	abnormal proprioceptive neuron morphology	J:182750
	abnormal sensory neuron innervation pattern	J:182750
Olig1tm1And/Olig1tm1And Olig2tm1And/Olig2tm1And involves: 129 * C57BL/6J	abnormal nervous system development	J:76446
	abnormal ventral interneuron 2 morphology	J:76446
	absent oligodendrocytes	J:76446
	decreased fetal size	J:76446
	decreased motor neuron number	J:76446
	decreased oligodendrocyte progenitor number	J:76446
	perinatal lethality, complete penetrance	J:76446
Olig1tm1And/Olig1tm1And Olig2tm1And/Olig2tm1And Tg(Olig2)#Wdr/? Not Specified	abnormal oligodendrocyte morphology	J:210099
Olig2tm1(cre)Tmj/Olig2+ Shhtm2Amc/Shhtm2Amc involves: 129S1/Sv * 129X1/SvJ	abnormal spinal cord lateral motor column morphology	J:277700
	decreased motor neuron number	J:277700
	normal nervous system phenotype	J:277700
Olig2tm1(cre)Tmj/Olig2+ Smn1tm1Jme/Smn1tm1Msd Grm7Tg(SMN2)89Ahmb/Grm7+ involves: 129 * 129P2/OlaHsd * FVB/N	postnatal lethality, complete penetrance	J:164292
Olig2tm1(cre)Tmj/Olig2+ Smn1tm1Jme/Smn1tm1Msd Grm7Tg(SMN2)89Ahmb/Grm7Tg(SMN2)89Ahmb involves: 129 * 129P2/OlaHsd * FVB/N	abnormal CNS synaptic transmission	J:164292
	abnormal miniature endplate potential	J:164292
	abnormal muscle morphology	J:164292
	abnormal neuromuscular synapse morphology	J:164292
	abnormal PNS synaptic transmission	J:164292
	abnormal sensory neuron innervation pattern	J:164292
	abnormal synaptic bouton morphology	J:164292
	abnormal synaptic transmission	J:164292
	decreased body weight	J:164292
	decreased grip strength	J:164292
	decreased skeletal muscle fiber number	J:164292
	decreased survivor rate	J:164292
	increased skeletal muscle fiber size	J:164292
	kyphosis	J:164292
	motor neuron degeneration	J:164292
	muscle weakness	J:164292
	muscular atrophy	J:164292
	premature death	J:164292
	skeletal muscle fiber degeneration	J:164292
Prrc2atm1Fcw/Prrc2atm1Fcw Olig2tm2(TVA,cre)Rth/Olig2+ involves: 129 * C57BL/6	abnormal brain morphology	J:301796
	abnormal corpus callosum morphology	J:301796
	decreased body weight	J:301796
	decreased grip strength	J:301796
	decreased oligodendrocyte number	J:301796
	decreased oligodendrocyte progenitor number	J:301796
	dysmyelination	J:301796
	enlarged lateral ventricles	J:301796
	impaired coordination	J:301796
	impaired spatial learning	J:301796
	increased brain weight	J:301796
	normal nervous system phenotype	J:301796
	premature death	J:301796