Apln Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Apln
apelin
MGI:1353624

14 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Apln^tm1Ntak/Apln^tm1Ntak involves: 129X1/SvJ * C57BL/6J	anophthalmia	J:131824
	decreased capillary density	J:131824
	normal embryo phenotype	J:131824
	vascular stenosis	J:131824
	weight loss	J:131824
Apln^tm1Pngr/Y involves: 129P2/OlaHsd * C57BL/6	normal behavior/neurological phenotype	J:140286
	normal cardiovascular system phenotype	J:140286
	decreased ventricle muscle contractility	J:140286
	normal growth/size/body region phenotype	J:140286
	increased response of heart to induced stress	J:140286
Apln^tm1Pngr/Apln^tm1Pngr involves: 129P2/OlaHsd * C57BL/6	normal behavior/neurological phenotype	J:140286
	normal cardiovascular system phenotype	J:140286
	decreased ventricle muscle contractility	J:140286
	normal growth/size/body region phenotype	J:140286
Apln^tm1Tq/Y B6.129S6-Apln^tm1Tq	abnormal myocardial fiber physiology	J:154303
	decreased cardiac muscle contractility	J:154303
	decreased oxygen consumption	J:154303
	impaired exercise endurance	J:154303
Apln^tm1Tq/Apln^tm1Tq B6.129S6-Apln^tm1Tq	abnormal myocardial fiber physiology	J:154303
	decreased cardiac muscle contractility	J:154303
	decreased oxygen consumption	J:154303
	impaired exercise endurance	J:154303

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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